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Himalayas, on the southern rim of the Tibetan Plateau. Humans are generally adapted to lowland environments where oxygen is abundant. [12] At altitudes above 2,500 meters (8,200 ft), such humans experience altitude sickness, which is a type of hypoxia, a clinical syndrome of severe lack of oxygen.
Flies are common in the Himalayas up to 6,300 m (20,700 ft). [13] Bumble bees were discovered on Mount Everest at more than 5,600 m (18,400 ft) above sea level. [14] In subsequent tests, bumblebees were still able to fly in a flight chamber which recreated the thinner air of 9,000 m (30,000 ft). [15]
For endurance events (races of 800 metres or more), the predominant effect is the reduction in oxygen, which generally reduces the athlete's performance at high altitude. [54] One way to gauge this reduction is by monitoring VO 2 max, a measurement of the maximum capacity of an individual to utilize O 2 during strenuous exercise.
In 2005, at the age of 19, Tashi, who goes by his first name, became the youngest person to climb Mount Everest without bottled oxygen. Nepali Sherpas wait, grow potatoes as Himalayas remain ...
Hypoxic ventilatory response (HVR) is the increase in ventilation induced by hypoxia that allows the body to take in and transport lower concentrations of oxygen at higher rates. It is initially elevated in lowlanders who travel to high altitude, but reduces significantly over time as people acclimatize.
Himalayas from Kullu Valley, Himachal Pradesh. Also called the Mahabharat Range, the Lesser Himalayas is a prominent range 2,000 to 3,000 meters (6,600 to 9,800 ft) high formed along the Main Boundary Thrust fault zone, with a steep southern face and gentler northern slopes. The range is nearly continuous except for river gorges, where groups ...
Bottled oxygen can help mountaineers survive in the death zone. Mountaineers use supplemental oxygen in the death zone to reduce deleterious effects. An open-circuit oxygen apparatus was first tested on the 1922 and 1924 British Mount Everest expeditions; the bottled oxygen taken in 1921 was not used (see George Finch and Noel Odell).
2034 13819 Ensembl ENSG00000116016 ENSMUSG00000024140 UniProt Q99814 P97481 RefSeq (mRNA) NM_001430 NM_010137 RefSeq (protein) NP_001421 NP_034267 Location (UCSC) Chr 2: 46.29 – 46.39 Mb Chr 17: 87.06 – 87.14 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Endothelial PAS domain-containing protein 1 (EPAS1, also known as hypoxia-inducible factor-2alpha (HIF-2α)) is a protein ...