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Soman (or GD, EA 1210, Zoman, PFMP, A-255, systematic name: O-pinacolyl methylphosphonofluoridate) [1] is an extremely toxic chemical substance. It is a nerve agent , interfering with normal functioning of the mammalian nervous system by inhibiting the enzyme cholinesterase .
The blood of people killed by blood agents is bright red, because the agents inhibit the use of the oxygen in it by the body's cells. [2] Cyanide poisoning can be detected by the presence of thiocyanate or cyanide in the blood, a smell of bitter almonds, or respiratory tract inflammations and congestions in the case of cyanogen chloride ...
An Astrocyte, a cell notable for maintaining the blood brain barrier. Ammonia toxicity is often seen through two routes of administration, either through consumption or through endogenous ailments such as liver failure. [89] [90] One notable case in which ammonia toxicity is common is in response to cirrhosis of the liver which results in ...
An example is through the nicotinic acetylcholine receptor (nAchRs), which is a receptor commonly found along the surfaces of the cells that respond to nicotine stimulation, turning them on or off. Aβ was found manipulating the level of nicotine in the brain along with the MAP kinase , another signaling receptor, to cause cell death.
The blood–brain barrier (BBB) is a highly selective semipermeable border of endothelial cells that regulates the transfer of solutes and chemicals between the circulatory system and the central nervous system, thus protecting the brain from harmful or unwanted substances in the blood. [1]
A chemical weapon agent (CWA), or chemical warfare agent, is a chemical substance whose toxic properties are meant to kill, injure or incapacitate human beings.About 70 different chemicals have been used or stockpiled as chemical weapon agents during the 20th century, although the Organisation for the Prohibition of Chemical Weapons (OPCW) has an online database listing 35,942 chemicals which ...
Phoratoxin is hemolytic and causes cell leakage and cell lysis by interacting with the phospholipids. [8] This is used in a study for cancer treatment. The phoratoxin lyses the cancer cells, killing them. It supposedly helps with the chemotherapy and radiation as well, but little research has been done on this subject.
Chronic solvent-induced encephalopathy (CSE) is a condition induced by long-term exposure to organic solvents, often—but not always—in the workplace, that lead to a wide variety of persisting sensorimotor polyneuropathies and neurobehavioral deficits even after solvent exposure has been removed.