Search results
Results from the WOW.Com Content Network
Neuronal fear pathways [ edit ] In fear conditioning, the main circuits that are involved are the sensory areas that process the conditioned and unconditioned stimuli, certain regions of the amygdala that undergo plasticity (or long-term potentiation) during learning, and the regions that bear an effect on the expression of specific conditioned ...
The mesolimbic pathway and a specific set of the pathway's output neurons (e.g. D1-type medium spiny neurons within the nucleus accumbens) play a central role in the neurobiology of addiction. [ 20 ] [ 21 ] [ 22 ] Drug addiction is an illness caused by habitual substance use that induces chemical changes in the brain's circuitry. [ 23 ]
Pavlovian fear conditioning is a behavioral paradigm in which organisms learn to predict aversive events. [1] It is a form of learning in which an aversive stimulus (e.g. an electrical shock) is associated with a particular neutral context (e.g., a room) or neutral stimulus (e.g., a tone), resulting in the expression of fear responses to the originally neutral stimulus or context.
Joseph E. LeDoux (born December 7, 1949) is an American neuroscientist whose research is primarily focused on survival circuits, including their impacts on emotions such as fear and anxiety. [1]
Brief activation of an excitatory pathway can produce what is known as long-term depression (LTD) of synaptic transmission in many areas of the brain. LTD is induced by a minimum level of postsynaptic depolarization and simultaneous increase in the intracellular calcium concentration at the postsynaptic neuron.
Dopaminergic pathways (dopamine pathways, dopaminergic projections) in the human brain are involved in both physiological and behavioral processes including movement, cognition, executive functions, reward, motivation, and neuroendocrine control. [1] Each pathway is a set of projection neurons, consisting of individual dopaminergic neurons.
According to the hypothesis, two distinct pathways reactivate somatic marker responses. In the first pathway, emotion can be evoked by changes in the body that are projected to the brain – called the "body loop". For instance, encountering a feared object like a snake may initiate the fight-or-flight response and cause fear.
Frontostriatal circuits are neural pathways that connect frontal lobe regions with the striatum and mediate motor, cognitive, and behavioural functions within the brain. [1] They receive inputs from dopaminergic, serotonergic, noradrenergic, and cholinergic cell groups that modulate information processing. [2]