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  2. Human germline engineering - Wikipedia

    en.wikipedia.org/wiki/Human_germline_engineering

    The impact of human gene editing on resistance to HIV infection and other body functions in experimental infants remains controversial. The World Health Organization has issued three reports on the guidelines of human genome editing since 2019, [41] and the Chinese government has prepared regulations since May 2019. [42]

  3. Genome editing - Wikipedia

    en.wikipedia.org/wiki/Genome_editing

    Genome editing, or genome engineering, or gene editing, is a type of genetic engineering in which DNA is inserted, deleted, modified or replaced in the genome of a living organism. Unlike early genetic engineering techniques that randomly inserts genetic material into a host genome, genome editing targets the insertions to site-specific locations.

  4. CRISPR gene editing - Wikipedia

    en.wikipedia.org/wiki/CRISPR_gene_editing

    CRISPR-Cas9 genome editing techniques have many potential applications. The use of the CRISPR-Cas9-gRNA complex for genome editing [10] was the AAAS's choice for Breakthrough of the Year in 2015. [11] Many bioethical concerns have been raised about the prospect of using CRISPR for germline editing, especially in human embryos. [12]

  5. Human genetic enhancement - Wikipedia

    en.wikipedia.org/wiki/Human_genetic_enhancement

    With the discovery of various types of immune-related disorders, there is a need for diversification in prevention and treatment. Developments in the field of gene therapy are being studied to be included in the scope of this treatment, but of course more research is needed to increase the positive results and minimize the negative effects of gene therapy applications. [27]

  6. Genetic engineering - Wikipedia

    en.wikipedia.org/wiki/Genetic_engineering

    This is an accepted version of this page This is the latest accepted revision, reviewed on 19 January 2025. Manipulation of an organism's genome For a non-technical introduction to the topic of genetics, see Introduction to genetics. For the song by Orchestral Manoeuvres in the Dark, see Genetic Engineering (song). For the Montreal hardcore band, see Genetic Control. Part of a series on ...

  7. Genetic engineering techniques - Wikipedia

    en.wikipedia.org/wiki/Genetic_engineering_techniques

    The creation of HIV-resistant babies by Chinese researcher He Jiankui is perhaps the most famous example of gene disruption using this method. [68] It is far less effective at gene correction. Methods of base editing are under development in which a “nuclease-dead” Cas 9 endonuclease or a related enzyme is used for gene targeting while a ...

  8. Gene therapy - Wikipedia

    en.wikipedia.org/wiki/Gene_therapy

    In October, biophysicist and biohacker Josiah Zayner claimed to have performed the very first in-vivo human genome editing in the form of a self-administered therapy. [249] [250] On 13 November, medical scientists working with Sangamo Therapeutics, headquartered in Richmond, California, announced the first ever in-body human gene editing therapy.

  9. Gene editing - Wikipedia

    en.wikipedia.org/wiki/Gene_editing

    Gene editing may refer to: . Genetic engineering of any organism by genome editing. Gene editing is the emerging molecular biology technique which makes very specific targeted changes by insertion, deletion or substitution of genetic material in an organism's DNA to obtain desired results.