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Hydroxycarboxylic acid receptor 3 (HCA 3), also known as niacin receptor 2 (NIACR2) and GPR109B, [5] is a protein which in humans is encoded by the HCAR3 gene. [ 6 ] [ 7 ] HCA 3 , like the other hydroxycarboxylic acid receptors HCA 1 and HCA 2 , is a G i/o -coupled G protein-coupled receptor (GPCR).
The hydroxycarboxylic acid receptor (abbreviated HCA receptor and HCAR) family includes the following human proteins: [1] Hydroxycarboxylic acid receptor 1 (HCA 1 , formerly known as GPR81) Hydroxycarboxylic acid receptor 2 (HCA 2 , formerly known as niacin receptor 1 and GPR109A)
3-Hydroxyoctanoic acid is a beta-hydroxy acid that is naturally produced in humans, other animals, and plants. 3-Hydroxyoctanoic acid is the primary endogenous agonist of hydroxycarboxylic acid receptor 3 (HCA 3 ), a G protein-coupled receptor protein which is encoded by the human gene HCAR3 .
CA3 has been implicated in a number of working theories on memory and hippocampal learning processes. Slow oscillatory rhythms (theta-band; 3–8 Hz) are cholinergically driven patterns that depend on coupling of interneurons and pyramidal cell axons via gap junctions, as well as glutaminergic (excitatory) and GABAergic (inhibitory) synapses.
Helped by two Ohio State pass interference penalties, Texas stood 3 feet from a game-tying score. Ohio State held the line on first down, before Texas called a risky toss sweep on second down that ...
A number of car models won't ring in the new year.. The Ford Edge, Toyota Venza and Mini Clubman are just some of the vehicles that won't make it past model year 2024 in U.S. markets.
The goal of Nabbout’s study, the lead researcher told CNN, is to help regulators in the United States as they continue to make decisions about which products should remain on the market.
HCA 2 is expressed by: 1) certain cells in the immune system, e.g., neutrophils, monocytes, macrophages, dermal dendritic cells, [18] and lymphocytes; [13] 2) cells in the small intestine and colon epithelum that face the intestinal lumen; [26] 3) the skin's epithelial cells, keratinocytes, and Langerhans cells; [27] 4) brown and white adipose tissue fat cells; [28] 5) cells in the mammary ...