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Listening to Prozac: A Psychiatrist Explores Antidepressant Drugs and the Remaking of the Self is a book written by psychiatrist Peter D. Kramer. Written in 1993, the book discusses how the advance of the anti-depressant drug Prozac might change the way we see personality, the relationship between neurology and personality .
The UK National Institute for Health and Care Excellence (NICE)'s 2022 guidelines indicate that antidepressants should not be routinely used for the initial treatment of mild depression, "unless that is the person's preference". [29] The guidelines recommended that antidepressant treatment be considered:
Most of the weight gain caused by antidepressants is mild, with a 2017 study from Australia finding that high-dosage antidepressant users gain 0.28kg (about 0.6 lbs) per year on average.
Most antidepressants will hinder the breakdown of serotonin, norepinephrine, and/or dopamine. A commonly used class of antidepressants are called selective serotonin reuptake inhibitors (SSRIs), which act on serotonin transporters in the brain to increase levels of serotonin in the synaptic cleft . [ 22 ]
To get antidepressants, you’ll first need a prescription. Primary care providers (PCPs), psychiatric nurse practitioners, and psychiatrists are all qualified to prescribe antidepressant medications.
Antidepressants are recommended as an alternative or additional first step to self-help programs in the treatment of bulimia nervosa. [37] SSRIs (fluoxetine in particular) are preferred over other anti-depressants due to their acceptability, tolerability, and superior reduction of symptoms in short-term trials.
Sertraline, sold under the brand name Zoloft among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. [10] The effectiveness of sertraline for depression is similar to that of other antidepressants such as Fluoxetine or Paroxetine. Sertraline is better tolerated than the older tricyclic antidepressants.
There were an estimated 21.4 million antidepressant drugs items prescribed to patients in England between July and September 2022, according to data from the NHS Business Services Authority.
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