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The cell cycle, or cell-division cycle, is the sequential series of events that take place in a cell that causes it to divide into two daughter cells. These events include the growth of the cell, duplication of its DNA ( DNA replication ) and some of its organelles , and subsequently the partitioning of its cytoplasm, chromosomes and other ...
Regulator of chromosome condensation 1, also known as RCC1, Ran guanine nucleotide exchange factor and RanGEF, is the name for a human gene and protein. [ 5 ] RCC1 also functions as a guanine nucleotide exchange factor for Ran GTPase .
Genes are inherited as units, with two parents dividing out copies of their genes to their offspring. Humans have two copies of each of their genes, but each egg or sperm cell only gets one of those copies for each gene. An egg and sperm join to form a zygote with a complete set of genes. The resulting offspring has the same number of genes as ...
The total length of the human reference genome does not represent the sequence of any specific individual, nor does it represent the sequence of all of the DNA found within a cell. The human reference genome only includes one copy of each of the paired, homologous autosomes plus one copy of each of the two sex chromosomes (X and Y).
Checkpoint kinase 1, commonly referred to as Chk1, is a serine/threonine-specific protein kinase that, in humans, is encoded by the CHEK1 gene. [5] [6] Chk1 coordinates the DNA damage response (DDR) and cell cycle checkpoint response. [7]
G 1 phase is particularly important in the cell cycle because it determines whether a cell commits to division or to leaving the cell cycle. [2] If a cell is signaled to remain undivided, instead of moving onto the S phase, it will leave the G 1 phase and move into a state of dormancy called the G 0 phase.
In the whole cycle, gametes are usually the only haploid cells, and mitosis usually occurs only in the diploid phase. The diploid multicellular individual is a diplont, hence a gametic meiosis is also called a diplontic life cycle. Diplonts are: In archaeplastidans: some green algae (e.g., Cladophora glomerata, [15] Acetabularia [8] [9])
The repressor genes E2F7/E2F8, located on chromosome 7, are transcription factors responsible for protein coding cell cycle regulation. Together, they are essential for the development of an intact, organized, and functional placental structure during embryonic development.