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In some cases, the akathisia effects of metoclopramide are directly related to the infusion rate when the drug is administered intravenously. Side effects were usually seen in the first 15 minutes after administering the dose of metoclopramide. [30] Withdrawal effects were reported for a female taking metoclopramide for about six months.
Other anti-dopaminergic drugs, like the antiemetic metoclopramide, can also result in extrapyramidal side effects. [6] Short and long-term use of antidepressants such as selective serotonin reuptake inhibitors (SSRI), serotonin-norepinephrine reuptake inhibitors (SNRI), and norepinephrine-dopamine reuptake inhibitors (NDRI) have also resulted ...
The combination of metoclopramide to the paracetamol has been shown to enhance the analgesia relief when used to treat the pain of arthritis. [ 4 ] Whilst the individual component drugs may be prescribed individually, as a combination, it is only available as the branded Paramax preparation in the UK. [ 5 ]
Haloperidol (limited in usefulness by extra-pyramidal and sedative side-effects) Alizapride; Prochlorperazine (Compazine, Stemzine, Buccastem, Stemetil, Phenotil) Chlorpromazine (Use limited by sedating properties) Metoclopramide; NK1 receptor antagonist. Aprepitant (Emend) is a commercially available NK1 receptor antagonist
Certain prokinetic drugs such as cisapride, renzapride and metoclopramide, although not 5-HT 3 antagonists proper, possess some weak antagonist effect at the 5-HT 3 receptor. Galanolactone, a diterpenoid found in ginger, is a 5-HT 3 antagonist and is believed to at least partially mediate the anti-emetic activity of this plant.
Women are twice as likely to have an eating disorder in their 40s as to have breast cancer, but midlife eating disorders are under-researched and overlooked.
Less-common side effects can include excess air or gas in your stomach, burping, heartburn, indigestion, fast heartbeat, low blood sugar, low energy and fatigue, or even gallstones, Dr. Comite says.
Common side effects include blurred vision, dry mouth, sleepiness, constipation, and confusion. [2] It should not be used in people with a bowel obstruction or glaucoma. [2] It is unclear if use in pregnancy or breastfeeding is safe. [4] Biperiden is in the anticholinergic family of medication. [2]