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The purpose of the scheme is to achieve a balance between reasonable prices for the NHS and a fair return for the pharmaceutical industry. The current PPRS scheme, using a value-based pricing mechanism, came into effect on 1 January 2014, to run for no less than five years. [1] It replaced an earlier scheme running from 2009 to 2013. [2]
Formulations are 500/1, 500/2, 500/4, 1000/2, and 1000 mg/4 mg of metformin/rosiglitazone. In 2009, it was the most popular metformin combination. [183] In 2005, the stock of Avandamet was removed from the market, after inspections showed the factory where it was produced was violating good manufacturing practices. [184]
First released in 1999, annual sales peaked at approximately $2.5-billion in 2006; however, following a meta-analysis in 2007 that linked the drug's use to an increased risk of heart attack, [1] sales plummeted to just $9.5-million in 2012. The drug's patent expired in 2012. [2] It was patented in 1987 and approved for medical use in 1999. [3]
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The Invergordon Common Good Fund owns the bust, which was purchased in 1930 for about $6.35. Now, the historical bust could sell for $3.1 million.
Authorities confirmed to Fox News Digital that the 41-year-old migrant was intoxicated when he T-boned Christina Smith and her daughter Ivory at 2:45 a.m. Police said that Chacin took photographs ...
A viral post shared on X claims Florida Republican Rep. Matt Gaetz purportedly made a tweet about “age gap dating.” View on Threads Verdict: False The claim is false. The purported tweet was ...
Vildagliptin/metformin is indicated in the treatment of type-2 diabetes mellitus: [4] [6] [7] it is indicated in the treatment of adults who are unable to achieve sufficient glycaemic control at their maximally tolerated dose of oral metformin alone or who are already treated with the combination of vildagliptin and metformin as separate tablets.
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