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2. Equianalgesic - Wikipedia

   en.wikipedia.org/wiki/Equianalgesic

   Acute use (1–3 days) yields a potency about 1.5× stronger than that of morphine and chronic use (7 days+) yields a potency about 2.5 to 5× that of morphine. Similarly, the effect of tramadol increases after consecutive dosing due to the accumulation of its active metabolite and an increase of the oral bioavailability in chronic use.

3. List of Schedule III controlled substances (U.S.) - Wikipedia

   en.wikipedia.org/wiki/List_of_Schedule_III...

   Not more than 1.8 grams of codeine per 100 milliliters or not more than 90 milligrams per dosage unit, with an equal or greater quantity of an isoquinoline alkaloid of opium [4] [note 1] 9804 Not more than 1.8 grams of codeine per 100 milliliters or not more than 90 milligrams per dosage unit, with one or more active, nonnarcotic ingredients in ...

4. Dosage form - Wikipedia

   en.wikipedia.org/wiki/Dosage_form

   Dosage forms (also called unit doses) are pharmaceutical drug products presented in a specific form for use. They contain a mixture of active ingredients and inactive components ( excipients ), configured in a particular way (such as a capsule shell) and apportioned into a specific dose .

5. Rumack–Matthew nomogram - Wikipedia

   en.wikipedia.org/wiki/Rumack–Matthew_nomogram

   [1] [2] [3] This nomogram allows for timely management of an acetaminophen overdose. Generally, a serum plasma concentration (APAP) of 140–150 μg/mL (or mg/L) at 4 hours post-ingestion indicates the need for NAC treatment.

6. Paracetamol - Wikipedia

   en.wikipedia.org/wiki/Paracetamol

   Those who take it regularly at a higher dose (more than 2–3 g daily) are at much higher risk (3.6–3.7 times) of gastrointestinal bleeding and other bleeding events. [82] Meta-analyses suggest that paracetamol may increase the risk of kidney impairment by 23 % [83] and kidney cancer by 28 %. [81]

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