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White matter is the tissue through which messages pass between different areas of grey matter within the central nervous system. The white matter is white because of the fatty substance (myelin) that surrounds the nerve fibers (axons). This myelin is found in almost all long nerve fibers, and acts as an electrical insulation.
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Myelin is formed by oligodendrocytes in the central nervous system and Schwann cells in the peripheral nervous system.Therefore, the first stage of myelinogenesis is often defined as the differentiation of oligodendrocyte progenitor cells (OPCs) or Schwann cell progenitors into their mature counterparts, [4] followed by myelin formation around axons.
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Being rich in lipid, myelin appears white, hence the name given to the "white matter" of the CNS. Both CNS white matter tracts (e.g. the optic nerve, corticospinal tract and corpus callosum) and PNS nerves (e.g. the sciatic nerve and the auditory nerve, which also appear white) each comprise thousands to millions of axons, largely aligned in ...
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Myelination is only prevalent in a few brain regions at birth and continues into adulthood. The entire process is not complete until about 25–30 years of age. [24] Myelination is an important component of intelligence, and white matter quantity may be positively correlated with IQ test results in children. [24]
Myelination is a process by which axons are covered with a protective substance called myelin that drastically increases the signaling efficiency of the neuron. [7] The arcuate fasciculus is heavily myelinated in healthy adult brains. The density of this myelination has been found to predict the accuracy and speed to which one can comprehend ...