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  2. Hypothyroidism - Wikipedia

    en.wikipedia.org/wiki/Hypothyroidism

    Subclinical hypothyroidism is a biochemical diagnosis characterized by an elevated serum TSH level, but with a normal serum free thyroxine level. [47] [48] [49] The incidence of subclinical hypothyroidism is estimated to be 3-15% and a higher incidence is seen in elderly people, females and those with lower iodine levels. [47]

  3. Thyroid function tests - Wikipedia

    en.wikipedia.org/wiki/Thyroid_function_tests

    Thyroid function tests (TFTs) is a collective term for blood tests used to check the function of the thyroid. [1] TFTs may be requested if a patient is thought to suffer from hyperthyroidism (overactive thyroid) or hypothyroidism (underactive thyroid), or to monitor the effectiveness of either thyroid-suppression or hormone replacement therapy.

  4. Thyroid-stimulating hormone - Wikipedia

    en.wikipedia.org/wiki/Thyroid-stimulating_hormone

    TSH Isomers - natural variations of the TSH molecule, which have lower activity, so the pituitary gland would need to produce more TSH to obtain the same overall level of TSH activity. [ 24 ] [ 25 ] The same TSH concentration may have a different meaning whether it is used for diagnosis of thyroid dysfunction or for monitoring of substitution ...

  5. Jostel's TSH index - Wikipedia

    en.wikipedia.org/wiki/Jostel's_TSH_index

    Negative correlation of Jostel's TSH index to the urinary excretion of certain phthalates suggests that endocrine disruptors may affect the central set point of thyroid homeostasis. [28] Drugs that reduce the TSH index, probably via effects on the central set point of the feedback loop, include mirtazapine [29] and oxcarbazepine. [30]

  6. TRH stimulation test - Wikipedia

    en.wikipedia.org/wiki/TRH_stimulation_test

    Therefore, when TRH is given exogenously, TSH levels increase. If the increase in serum TSH level following TRH administration is absent or very slight, then the cause of the hypothyroidism is in the anterior pituitary gland, i.e. the pituitary is not secreting TSH. Therefore, even when TRH is given exogenously, TSH levels do not rise as the ...

  7. Releasing and inhibiting hormones - Wikipedia

    en.wikipedia.org/wiki/Releasing_and_inhibiting...

    For example, thyrotropin-releasing hormone (TRH) is released from the hypothalamus in response to low levels of secretion of thyroid-stimulating hormone (TSH) from the pituitary gland. The TSH in turn is under feedback control by the thyroid hormones T4 and T3. When the level of TSH is too high, they feed back on the brain to shut down the ...

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