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  2. Antithyroid autoantibodies - Wikipedia

    en.wikipedia.org/wiki/Antithyroid_autoantibodies

    Antithyroid autoantibodies (or simply antithyroid antibodies) are autoantibodies targeted against one or more components on the thyroid.The most clinically relevant anti-thyroid autoantibodies are anti-thyroid peroxidase antibodies (anti-TPO antibodies, TPOAb), thyrotropin receptor antibodies (TRAb) and thyroglobulin antibodies (TgAb).

  3. Thyroglobulin - Wikipedia

    en.wikipedia.org/wiki/Thyroglobulin

    Thyroglobulin (Tg) is a 660 kDa, dimeric glycoprotein produced by the follicular cells of the thyroid and used entirely within the thyroid gland. Tg is secreted and accumulated at hundreds of grams per litre in the extracellular compartment of the thyroid follicles, accounting for approximately half of the protein content of the thyroid gland. [5]

  4. Thyroid peroxidase - Wikipedia

    en.wikipedia.org/wiki/Thyroid_peroxidase

    Thyroid peroxidase is a frequent epitope of autoantibodies in autoimmune thyroid disease, with such antibodies being called anti-thyroid peroxidase antibodies (anti-TPO antibodies). This is most commonly associated with Hashimoto's thyroiditis. Thus, an antibody titer can be used to assess disease activity in patients that have developed such ...

  5. What Getting 105 Blood Tests From a Health Startup Taught Me

    www.aol.com/getting-105-blood-tests-health...

    I learned, for example, that my thyroglobulin antibodies (TgAb) were above range—“low-grade Hashimoto’s,” Hyman speculated after reviewing my results—and that I had ketones and “many ...

  6. Hashimoto's thyroiditis - Wikipedia

    en.wikipedia.org/wiki/Hashimoto's_thyroiditis

    The two antibodies most commonly implicated in autoimmune thyroiditis are thyroid peroxidase antibodies and thyroglobulin antibodies. [5] They are hypothesized to develop as a result of thyroid damage, where T-lymphocytes are sensitized to residual thyroid peroxidase and thyroglobulin, rather than as the cause of thyroid damage. [ 5 ]

  7. Antithyroid agent - Wikipedia

    en.wikipedia.org/wiki/Antithyroid_agent

    They inhibit release of thyroid hormones by the thyroid gland.The most studied drug in this class is lithium, which inhibits thyroid hormone secretion by inhibiting iodotyrosine coupling, thyroidal iodide uptake, and alteration in structure of thyroglobulin, [10] a protein which acts as a substrate for the synthesis of thyroid hormones and storage of inactive forms of T3, T4 and iodine within ...

  8. Graves' disease - Wikipedia

    en.wikipedia.org/wiki/Graves'_disease

    Graves' disease is an autoimmune disorder, in which the body produces antibodies that are specific to a self-protein - the receptor for thyroid-stimulating hormone. (Antibodies to thyroglobulin and to the thyroid hormones T3 and T4 may also be produced.) These antibodies cause hyperthyroidism because they bind to the TSHr and chronically ...

  9. Hashimoto's encephalopathy - Wikipedia

    en.wikipedia.org/wiki/Hashimoto's_encephalopathy

    Between 1990 and 2000, 43 cases were published. Since that time, research has expanded and numerous cases are being reported by scientists around the world, suggesting that this rare condition is likely to have been significantly undiagnosed in the past. Over 100 scientific articles on Hashimoto's encephalopathy were published between 2000 and ...

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