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Phenylketonuria (PKU)-like symptoms, including more pronounced developmental defects, skin irritation, and vomiting, may appear when phenylalanine levels are near 20 mg/dL (1200 mol/L). [1] Hyperphenylalaninemia is a recessive hereditary metabolic disorder that is caused by the body's failure to convert phenylalanine to tyrosine as a result of ...
Tetrahydrobiopterin deficiency (THBD, BH 4 D) is a rare metabolic disorder that increases the blood levels of phenylalanine.Phenylalanine is an amino acid obtained normally through the diet, but can be harmful if excess levels build up, causing intellectual disability and other serious health problems.
The absence of BH 4 affects the metabolism of Phenylalanine. This is the reason that PKU and PTPS deficiency share some similar symptoms. However, since BH 4 is needed for much more than just the metabolism of Phenylalanine, there are other symptoms as well. [7]
As explained above, Diet Coke and Coke Zero use different sweetening agents. Both have aspartame , which Brown explains is a low-calorie sweetener made of two amino acids (phenylalanine and ...
Soda gets a bad rep. For a long time, we've demonized sugar and regular Coca-Cola. Then came its sugar-free counterparts, Diet Coke and Coke Zero. But then we began to question their ingredients, too.
According to one of the largest, the landmark U.S. Framingham Heart Study, drinking just one can of soda daily has been linked to obesity, increased waist size, high blood pressure, high ...
A diet that is low in phenylalanine but does not include protein substitutes may also fail to lower blood Phe levels, since a nutritionally insufficient diet may also trigger catabolism. For all these reasons, the prescription formula is an important part of the treatment for patients with classic PKU.
In lieu of sugar, Diet Coke and Diet Pepsi employ aspartame, an artificial sweetener that imparts sweetness sans calories. Some other diet drinks on the market use different low- or no-cal ...