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The herpes virus can then exit this dormant stage and re-enter the lytic cycle, causing disease symptoms. Thus, while herpes viruses can enter both the lytic and lysogenic cycles, latency allows the virus to survive and evade detection by the immune system due to low viral gene expression. The model organism for studying lysogeny is the lambda ...
Viruses may undergo two types of life cycles: the lytic cycle and the lysogenic cycle. In the lytic cycle, the virus introduces its genome into a host cell and initiates replication by hijacking the host's cellular machinery to make new copies of the virus. [12] In the lysogenic life cycle, the viral genome is incorporated into the host genome.
Virus latency (or viral latency) is the ability of a pathogenic virus to lie dormant within a cell, denoted as the lysogenic part of the viral life cycle. [1] A latent viral infection is a type of persistent viral infection which is distinguished from a chronic viral infection. Latency is the phase in certain viruses' life cycles in which ...
Temperate phages can switch between a lytic and lysogenic life cycle. Lytic is more drastic, killing the host whereas lysogenic impacts host cells genetically or physiologically. [4] [5] [6] Here is a chart on temperate phages that are lytic and lysogenic and how they're related. Lysogeny is characterized by the integration of the phage genome ...
On initial infection, the stability of cII determines the lifestyle of the phage; stable cII will lead to the lysogenic pathway, whereas if cII is degraded the phage will go into the lytic pathway. Low temperature, starvation of the cells and high multiplicity of infection (MOI) are known to favor lysogeny (see later discussion).
In the lytic pathway, viral replication proceeds immediately following infection and releases approximately 300–500 phage progeny via cell lysis within an hour. [1] However, in the lysogenic pathway, the phage chromosome integrates into the host chromosome and is passed to daughter cells through cell division. [1]
Some viruses can "hide" within a cell, which may mean that they evade the host cell defenses or immune system and may increase the long-term "success" of the virus. This hiding is deemed latency. During this time, the virus does not produce any progeny, it remains inactive until external stimuli—such as light or stress—prompts it to activate.
A lysogen or lysogenic bacteria is a bacterial cell that can produce and transfer the ability to produce a phage. [1] A prophage is either integrated into the host bacteria 's chromosome or more rarely exists as a stable plasmid within the host cell.