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  2. Modified-release dosage - Wikipedia

    en.wikipedia.org/wiki/Modified-release_dosage

    Modified-release dosage is a mechanism that (in contrast to immediate-release dosage) delivers a drug with a delay after its administration (delayed-release dosage) or for a prolonged period of time (extended-release [ER, XR, XL] dosage) or to a specific target in the body (targeted-release dosage). [1] Sustained-release dosage forms are dosage ...

  3. Extended-release morphine - Wikipedia

    en.wikipedia.org/wiki/Extended-release_morphine

    Extended-release (or slow-release) formulations of morphine are those whose effect last substantially longer than bare morphine, availing for, e.g., one administration per day. Conversion between extended-release and immediate-release (or "regular") morphine is easier than conversion to or from an equianalgesic dose of another opioid with ...

  4. Pharmaceutical formulation - Wikipedia

    en.wikipedia.org/wiki/Pharmaceutical_formulation

    The dissolution time can be modified for a rapid effect or for sustained release. Special coatings can make the tablet resistant to the stomach acids such that it only disintegrates in the duodenum, jejunum and colon as a result of enzyme action or alkaline pH. Pills can be coated with sugar, varnish, or wax to disguise the taste ...

  5. Pill splitting - Wikipedia

    en.wikipedia.org/wiki/Pill_splitting

    A pill-splitter is a simple and inexpensive device to split medicinal pills or tablets, comprising some means of holding the tablet in place, a blade, and usually a compartment in which to store the unused part. The tablet is positioned, and the blade pressed down to split it. With care it is often possible to cut a tablet into quarters.

  6. Osmotic-controlled release oral delivery system - Wikipedia

    en.wikipedia.org/wiki/Osmotic-controlled_Release...

    The drug is expelled via the laser-drilled hole visible on the left side of the tablet. The osmotic-controlled release oral delivery system (OROS) is an advanced controlled release oral drug delivery system in the form of a rigid tablet with a semi-permeable outer membrane and one or more small laser drilled holes in it.

  7. Methylphenidate - Wikipedia

    en.wikipedia.org/wiki/Methylphenidate

    Metadate CD capsules contain two types of beads: 30% are immediate-release, and the other 70% are evenly sustained release. [185] Medikinet Retard/CR/Adult/Modified Release tablets are an extended-release oral capsule form of methylphenidate. It delivers 50% of the dosage as IR MPH and the remaining 50% in 3–4 hours. [186] [187]

  8. Is It Safe to Use Expired Vitamins? The Truth About Vitamin ...

    www.aol.com/vitamins-expire-nutritionists-weigh...

    When you buy a bottle of vitamins from a nutrition store, you’ll probably notice a best-by date on the bottom of the jar. But that inscribed number isn’t a hard-and-fast rule—there is some ...

  9. Bioavailability - Wikipedia

    en.wikipedia.org/wiki/Bioavailability

    The drug formulation (immediate release, excipients used, manufacturing methods, modified release – delayed release, extended release, sustained release, etc.) Whether the formulation is administered in a fed or fasted state; Gastric emptying rate; Circadian differences; Interactions with other drugs/foods: