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Hyperandrogenism, especially high levels of testosterone, can cause serious adverse effects if left untreated. High testosterone levels are associated with other health conditions such as obesity, hypertension, amenorrhea (cessation of menstrual cycles), and ovulatory dysfunction, which can lead to infertility.
Testosterone, via its active metabolite 3α-androstanediol, is a potent positive allosteric modulator of the GABA A receptor. [150] Testosterone has been found to act as an antagonist of the TrkA and p75 NTR, receptors for the neurotrophin nerve growth factor (NGF), with high affinity (around 5 nM).
[49] [28] High dosages of testosterone (with levels of > 50 ng/dL) have a risk of masculinization (e.g., acne, hair growth, voice changes) with long-term therapy in women. [49] [28] High dosages of testosterone but not low dosages of testosterone enhance the effects of low dosages of estrogens on sexual desire.
A new study found that older men with higher levels of circulating testosterone were at an increased risk for atrial fibrillation. High testosterone levels linked to increased risk of AFib in ...
In healthy older men, abnormal testosterone levels were associated with a greater risk of developing AFib, according to a new study. In healthy older men, abnormal testosterone levels were ...
‘We have high levels of testosterone in our 20s, but after the age of 30, levels naturally decline by approximately 1% per year - unless you have a surgically-induced menopause, during which ...
Testosterone poisoning is a popular term used to explain behaviors that are deemed excessively masculine. [1] It is also used by transfeminine people including transgender women and nonbinary individuals to describe the negative effects that testosterone has had on their bodies.
That said, not everything is simple. Red meat is high in trans fats, but also high in testosterone-promoting nutrients like zinc — as with everything, balance and moderation are the best strategies.
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