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Electrochemical aptamer-based (E-AB) biosensors is a device that takes advantage of the electrochemical and biological properties of aptamers to take real time, in vivo measurements. An electrochemical aptamer-based (E-AB) biosensor generates an electrochemical signal in response to specific target binding in vivo [ 3 ] The signal is measured ...
In amperometric biosensors, an enzyme-catalyzed redox reaction causes a redox electron current that is measured by a working electrode. [11] Amperometric biosensors have been used in bio-MEMS for detection of glucose , galactose , lactose , urea , and cholesterol , as well as for applications in gas detection and DNA hybridization . [ 11 ]
A notable recent application involves using laser-induced self-N-doped porous graphene in miRNA biosensors, capable of detecting miRNA hsa-miR-486-5p at concentrations as low as 10 fM. This approach combines cost-effectiveness with high reproducibility, offering significant advantages for conditions like preeclampsia.
[77] [78] Development of wearable biosensors is among such studies. [79] The elimination of lab testing can save time and money. An application of a POCT biosensor can be for the testing of HIV in areas where it is difficult for patients to be tested. A biosensor can be sent directly to the location and a quick and easy test can be used.
Also in 2015 another project announced a microsupercapacitor that is small enough to fit in wearable or implantable devices. Just one-fifth the thickness of a sheet of paper, it is capable of holding more than twice as much charge as a comparable thin-film lithium battery. The design employed laser-scribed graphene, or LSG with manganese ...
Biosensor used NLR (neutrophil-to-lymphocyte ratio) Elevates with inflammation caused by cancer [75] No Basic Fibroblast Growth Factor (bFGF) This level increases when a tumor is present, helps with the fast reproduction of tumor cells [76] Electrochemical [77] Insulin-like Growth Factor (IGF-R) High activity in cancer cells, help reproduction [78]
Cancer, a group of diseases in which cells grow and divide abnormally, is one of the primary diseases being looked at with regards to how it responds to CNT drug delivery. Current cancer therapy primarily involves surgery, radiation therapy, and chemotherapy. These methods of treatment are usually painful and kill normal cells in addition to ...
Another cancer related application, though still in mice probing stage, is the use of peptide-coated nanoparticles as activity-based sensors to detect lung cancer. The two main advantages of the use of nanoparticles to detect diseases is that it allows early stage detection, as it can detect tumors the size in the order of millimeters.