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The first four seem to be involved in the hydroxylation of toluene to benzyl alcohol. CYP2E1 seems to be the primary enzyme in the hydroxylation of toluene, accounting for roughly 44% of toluene metabolism; [1] however, there is a great deal of ethnic variability, in the Finnish population for example the primary enzyme is CYP2B6.
1 MSDS sheets. 2 Structure and ... Download as PDF; Printable version; ... This page provides supplementary chemical data on toluene. MSDS sheets. Structure and ...
Toluene is also found in cigarette smoke and car exhaust. If not in contact with air, toluene can remain unchanged in soil or water for a long time. [39] Toluene is a common solvent, e.g. for paints, paint thinners, silicone sealants, [40] many chemical reactants, rubber, printing ink, adhesives (glues), lacquers, leather tanners, and ...
The OSHA definition is part of a legal standard, which is the minimum legal requirement. Users or employers are encouraged to apply proper judgment to avoid taking unnecessary risks, even if the only immediate hazard is "reversible", such as temporary pain, disorientation, nausea, or non-toxic contamination.
The original edition, known as the Toxic Substances List was published on June 28, 1971, and included toxicological data for approximately 5,000 chemicals. The name changed later to its current name Registry of Toxic Effects of Chemical Substances. In January 2001 the database contained 152,970 chemicals.
This data is frequently screened for quality, relevancy and ideally contains data for species in multiple trophic levels and/or taxonomic groups. [1] [6] The lowest LC50 in the compiled database is then divided by the assessment factor to calculate the PNEC for that data. The assessment factor applied to acute toxicity data is typically 1000 ...
p-Toluic acid is an intermediate in the conversion of p-xylene to terephthalic acid, a commodity chemical used in the manufacture of polyethylene terephthalate.It is generated both by the oxidation of p-xylene as well as the hydrogenolysis of 4-carboxybenzaldehyde.
Chronic solvent-induced encephalopathy (CSE) is a condition induced by long-term exposure to organic solvents, often—but not always—in the workplace, that lead to a wide variety of persisting sensorimotor polyneuropathies and neurobehavioral deficits even after solvent exposure has been removed.