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Amyloid cardiomyopathy (stiff heart syndrome) [5] is a condition resulting in the death of part of the myocardium (heart muscle). It is associated with the systemic production and release of many amyloidogenic proteins, especially immunoglobulin light chain or transthyretin (TTR). [6]
The majority of treatment is aimed at preserving heart function and treating heart failure symptoms. [ 3 ] Light chain (AL-CM) Treatment: Since the cause of this subtype of cardiac amyloidosis is the excessive production of free light chains, the major goal of treatment is the reduction in concentration of light chains. [ 5 ]
Cardiomyopathy is a group of primary diseases of the heart muscle. [1] Early on there may be few or no symptoms. [1] As the disease worsens, shortness of breath, feeling tired, and swelling of the legs may occur, due to the onset of heart failure. [1]
There’s no reason to think the disease itself shortens life expectancy, however, Newsome says that some treatments for stiff-person syndrome could cut life short because they suppress the ...
Heart disease is a type of cardiovascular disease that affects the heart’s structure and function. ... Also known as “broken heart syndrome,” this type of cardiomyopathy is induced by ...
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Stiff-person syndrome (SPS), also known as stiff-man syndrome, [1] is a rare neurological disorder of unclear cause characterized by progressive muscular rigidity and stiffness. The stiffness primarily affects the truncal muscles and is characterised by spasms , resulting in postural deformities.
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