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Among the somatic effects, secondary cancer is the most important. It develops because radiation causes DNA mutations directly and indirectly. Direct effects are those caused by ionizing particles and rays themselves, while the indirect effects are those that are caused by free radicals, generated especially in water radiolysis and oxygen ...
The four trials are a Phase II/III in soft tissue sarcoma of the extremity and trunk wall, [9] a Phase I/II for hepatocellular carcinoma, [10] a Phase I/II for prostate cancer, [11] and a Phase I for squamous cell carcinoma of the oral cavity. [12] Nimoral Azanta This compound increases the yield of DNA damage from irradiation under hypoxic ...
Measurements of RBE with external sources also neglect the ionization caused by the recoil of the parent-nucleus due to the alpha decay. While the recoil of the parent-nucleus of the decaying atom typically carries only about 2% of the energy of the alpha-particle that is emitted by the decaying atom, its range is extremely short (about 2–3 ...
It is important to distinguish the radiosensitivity of a particular tumor, which to some extent is a laboratory measure, from the radiation "curability" of a cancer in actual clinical practice. For example, leukemias are not generally curable with radiation therapy, because they are disseminated through the body.
Higher levels of omega-6 fatty acids often found in ultraprocessed foods may interfere with the immune system’s fight against cancer cells, a new study says. Certain foods may disrupt your body ...
Early detection is widely seen as key to cancer survival, which is why screenings and prevention are so widely recommended. And the message seems to be getting across, according to a study led by ...
Another important observation is that oxygen must be present at irradiation or within milliseconds afterward for the oxygen effect to take place. [ 8 ] The best known explanation of the oxygen effect is the oxygen fixation hypothesis developed by Alexander in 1962, [ 9 ] which posited that radiation-induced non-restorable or "fixed" nuclear DNA ...
A new study adds to the large body of evidence that being in good physical shape can dramatically reduce cancer risk. The study, published Tuesday in the British Journal of Sports Medicine, found ...