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  2. Ramelteon - Wikipedia

    en.wikipedia.org/wiki/Ramelteon

    Ramelteon is an analogue of melatonin and is a selective agonist of the melatonin MT 1 and MT 2 receptors. [3] The half-life and duration of ramelteon are much longer than those of melatonin. [7] Ramelteon is not a benzodiazepine or Z-drug and does not interact with GABA receptors, instead having a distinct mechanism of action. [3] [8]

  3. Topiramate - Wikipedia

    en.wikipedia.org/wiki/Topiramate

    Topiramate itself is a weak inhibitor of CYP2C19 and induces CYP3A4; a decrease in plasma levels of estrogens and digoxin has been noted during topiramate therapy. This can reduce the effectiveness of oral contraceptives (birth control pills); use of alternative birth control methods is recommended. [ 55 ]

  4. Melatonin receptor agonist - Wikipedia

    en.wikipedia.org/wiki/Melatonin_receptor_agonist

    In 2005 ramelteon (Rozerem) was approved in the US indicated for treatment of insomnia, characterized as difficulty with falling asleep, in adults. [ citation needed ] Melatonin in the form of prolonged release (trade name Circadin ) was approved in 2007 in Europe (EU) for use as a short-term treatment, in patients 55 years or older, for ...

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    U.S. News & World Report just rated the Mediterranean diet as the No. 1 diet for the eighth year in a row. Not only did it win best overall diet, it also won the top spot for managing diabetes ...

  8. Tasimelteon - Wikipedia

    en.wikipedia.org/wiki/Tasimelteon

    Tasimelteon, sold under the brand name Hetlioz, is a medication approved by the U.S. Food and Drug Administration (FDA) [3] in January 2014, for the treatment of non-24-hour sleep–wake disorder (also called non-24, N24 and N24HSWD). [4]

  9. Harvey Fierstein Lost 120 lbs. on Zepbound: 'Being Fat Is Not ...

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    After gaining weight during the Covid-19 pandemic, Harvey Fierstein says that he’s now lost 120 lbs., — all thanks to weight-loss medication. In typically irreverent Fierstein fashion, the ...

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