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Typical antipsychotics (also known as major tranquilizers, and first generation antipsychotics) are a class of antipsychotic drugs first developed in the 1950s and used to treat psychosis (in particular, schizophrenia). Typical antipsychotics may also be used for the treatment of acute mania, agitation, and other conditions.
8.1.2 Medium potency. 8.1.3 High potency. 8.2 Atypical Antipsychotics. 8.3 Adjuncts. ... Typical antipsychotics. Low potency. INN Common brand names Chlorprothixene:
Antipsychotics by class Generic name Brand names Chemical class ATC code Typical antipsychotics; Acepromazine: Atravet, Acezine: phenothiazine: N05AA04
High-potency antipsychotics such as haloperidol, in general, have doses of a few milligrams and cause less sleepiness and calming effects than low-potency antipsychotics such as chlorpromazine and thioridazine, which have dosages of several hundred milligrams. The latter have a greater degree of anticholinergic and antihistaminergic activity ...
Find out what typical and atypical antipsychotics are, what they are used for, how they work, and their potential risks and benefits.
Saphris – atypical antipsychotic used to treat schizophrenia and bipolar disorder; Serax – anti-anxiety medication of the benzodiazepine class, often used to help during detoxification from alcohol or other addictive substances; Serentil (mesoridazine) – an antipsychotic drug used in the treatment of schizophrenia [1]
As haloperidol is a high-potency typical antipsychotic, it tends to produce significant extrapyramidal side effects. According to a 2013 meta-analysis of the comparative efficacy and tolerability of 15 antipsychotic drugs it was the most prone of the 15 for causing extrapyramidal side effects. [29]
Some scientists say loxapine is a "mid-potency" typical antipsychotic. [15] However, unlike most other typical antipsychotics, it has significant potency at the 5HT 2A receptor (6.6 nM), which is similar to atypical antipsychotics like clozapine (5.35 nM).