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  2. Cryoneurolysis - Wikipedia

    en.wikipedia.org/wiki/Cryoneurolysis

    Cryoneurolysis treatments that use nitrous oxide (boiling point of −88.5 °C) as the coolant fall in the range of an axonotmesis injury, or 2nd degree injury, according to the Sunderland classification system. [1] Treatments of the nerve in this temperature range are reversible, usually within a few months.

  3. Recreational use of nitrous oxide - Wikipedia

    en.wikipedia.org/wiki/Recreational_use_of...

    Long-term or habitual use can lead to severe neurological damage. [3] Nitrous oxide is said to enhance the effects of psychedelics. [6] Since nitrous oxide can cause dizziness, dissociation, and temporary loss of motor control, it is unsafe to inhale while standing up. Safer use can involve inhalation while seated to decrease risks of injury by ...

  4. Nitrous oxide - Wikipedia

    en.wikipedia.org/wiki/Nitrous_oxide

    Nitrous oxide is a colourless gas with a faint, sweet odour. Nitrous oxide supports combustion by releasing the dipolar bonded oxygen radical, and can thus relight a glowing splint. N 2 O is inert at room temperature and has few reactions. At elevated temperatures, its reactivity increases. For example, nitrous oxide reacts with NaNH

  5. Erythropoietin in neuroprotection - Wikipedia

    en.wikipedia.org/wiki/Erythropoietin_in_neuro...

    Cross-talk between JAK2 and NF-κB signaling cascades has been demonstrated to be a possible factor in central nerve injury. Erythropoietin has also been shown to prevent axonal degeneration when produced by neighboring Schwann cells with nitrous oxide as the axonal injury signal. [12]

  6. Fink effect - Wikipedia

    en.wikipedia.org/wiki/Fink_Effect

    It is for this reason that Entonox, a 50:50 gaseous mixture of nitrous oxide and oxygen, is suitable for use by para-medical staff such as ambulance officers: it provides sufficient nitrous oxide for pain relief with sufficient oxygen to avoid hypoxia. [7] [8]

  7. Subacute combined degeneration of spinal cord - Wikipedia

    en.wikipedia.org/wiki/Subacute_combined...

    Administration of nitrous oxide anesthesia can precipitate subacute combined degeneration in people with subclinical vitamin B 12 deficiency, while chronic nitrous oxide exposure can cause it even in persons with normal B 12 levels. Posterior column dysfunction decreases vibratory sensation and proprioception (joint sense).

  8. Neurotoxicity - Wikipedia

    en.wikipedia.org/wiki/Neurotoxicity

    As a result, the increased concentration of Ca 2+ directly increases the stress on mitochondria, resulting in excessive oxidative phosphorylation and production of reactive oxygen species (ROS) via the activation of nitric oxide synthase, ultimately leading to cell death. Aβ was also found aiding this route to neurotoxicity by enhancing neuron ...

  9. Complications of anesthetic gases - Wikipedia

    en.wikipedia.org/wiki/Complications_of...

    2.Leaks in the high pressure system between the nitrous oxide (N2O) cylinder, 3.Can escape from around the patient's anesthesia mask, 4.Can escape from around the patient's endotracheal tube 5.Can in an anesthetic medical procedure.

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