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In pharmacology, bioavailability is a subcategory of absorption and is the fraction (%) of an administered drug that reaches the systemic circulation. [1] By definition, when a medication is administered intravenously, its bioavailability is 100%.
The Chinese definition of "bioequivalence" entails having the test drug's geometric mean C max, AUC (0–t), and AUC (0–∞) fall into 80%–125% of the reference drug in both fasting and fed states. The reference drug should be preferably the original brand-name drug, then (if not available) an internationally-recognized generic approved by ...
Despite these challenges, children with SHCN fare better than non-affected children in preventative health care and preventative dental care. [3] They have a higher rate of having health insurance than normal children. [2] They more frequently complete the recommended annual primary care visit, and bi-annual dentist visit. [2]
The definition of the topical route of administration sometimes states that both the application location and the pharmacodynamic effect thereof is local. [3] In other cases, topical is defined as applied to a localized area of the body or to the surface of a body part regardless of the location of the effect.
They may enhance bioavailability of allopathic drugs, vitamins, nutrients and toxins depending on its mechanism of action. For example, piperine increases bioavailability of several nutrients such as beta-carotene, [ 3 ] vitamin A, vitamin B6, coenzyme Q10, [ 4 ] [ 5 ] drugs such as phenytoin, [ 6 ] theophylline , [ 7 ] propanolol [ 7 ] and a ...
According to the World Health Organization, "cervical cancer is the fourth most common cancer in women." An estimated 660,000 women were diagnosed with the cancer worldwide in 2022, and 350,000 ...
The recall is now Class I, meaning that "there is a reasonable probability that use of the product will cause serious, adverse health consequences or death," according to the Food Safety and ...
When Michael Adams was researching health insurance options in 2023, he had one very specific requirement: coverage for prosthetic limbs. The roughly $50,000 leg with the electronically controlled ...