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  2. Abituzumab - Wikipedia

    en.wikipedia.org/wiki/Abituzumab

    Abituzumab is a humanized IgG2 monoclonal antibody (mAb) targeted at CD51 (an integrin) currently in development by Merck KGaA Darmstadt, Germany in an attempt to prevent bone lesion metastases in castration-resistant prostate cancer. [1] [2]

  3. Ponsegromab - Wikipedia

    en.wikipedia.org/wiki/Ponsegromab

    Ponsegromab (PF-06946860) is a monoclonal antibody that works as a GDF-15 inhibitor. It is developed by Pfizer for cancer cachexia. [1] [2] [3] [4] [5]In September ...

  4. List of therapeutic monoclonal antibodies - Wikipedia

    en.wikipedia.org/wiki/List_of_therapeutic...

    This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs that have been withdrawn from market; consequently, the column Use does not necessarily indicate clinical usage. See the list of FDA-approved therapeutic monoclonal antibodies in the monoclonal antibody therapy page.

  5. Hospitals in New York region say they've run out of antibody ...

    www.aol.com/news/hospitals-york-region-theyve...

    Federal supply of the one monoclonal antibody treatment that has proven effective is now "limited," with more doses expected in January, a Health and Human Services spokesperson said.

  6. Ocaratuzumab - Wikipedia

    en.wikipedia.org/wiki/Ocaratuzumab

    Ocaratuzumab (AME-133v, LY2469298) is a humanized monoclonal antibody designed for the treatment of cancer and autoimmune disorders. [1] The antibody is engineered for enhanced affinity to the CD20 antigen on B-lymphocytes, increased antibody-dependent cell-mediated cytotoxicity (ADCC), and for improved treatment of low-affinity FcγRIIIa allotypes.

  7. Tocilizumab - Wikipedia

    en.wikipedia.org/wiki/Tocilizumab

    It is a recombinant humanized monoclonal antibody of the immunoglobulin IgG1 subclass against the interleukin-6 receptor (IL-6R). [18] Interleukin 6 (IL-6) is a cytokine that plays an important role in immune response and is implicated in the pathogenesis of many diseases, such as autoimmune diseases, multiple myeloma and prostate cancer.

  8. Indium (111In) capromab pendetide - Wikipedia

    en.wikipedia.org/wiki/Indium_(111In)_capromab...

    Capromab is a mouse monoclonal antibody which recognizes a protein found on both prostate cancer cells and normal prostate tissue. It is linked to pendetide , a derivative of DTPA . [ 2 ] Pendetide acts as a chelating agent for the radionuclide indium-111 .

  9. Cancer immunotherapy - Wikipedia

    en.wikipedia.org/wiki/Cancer_immunotherapy

    Monoclonal antibodies: designed to bind to specific targets on cancer cells, marking cancer cells so that they will be better seen and destroyed by the immune system. Treatment vaccines : also known as therapeutic cancer vaccines, help the immune system learn to recognize and react to mutant proteins specific to the tumor and destroy cancer ...

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