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Typhoid fever, also known simply as typhoid, is a disease caused by Salmonella enterica serotype Typhi bacteria, also called Salmonella typhi. [2] [3] Symptoms vary from mild to severe, and usually begin six to 30 days after exposure. [4] [5] Often there is a gradual onset of a high fever over several days. [4]
Typhoid Mary in a 1909 newspaper illustration. Mary Mallon was an asymptomatic carrier of Salmonella typhi who is thought to have infected 53 others with typhoid fever while continuing her work as a cook. An asymptomatic carrier is a person or other organism that has become infected with a pathogen, but shows no signs or symptoms. [1]
Mary Mallon (September 23, 1869 – November 11, 1938), commonly known as Typhoid Mary, was an Irish-born American cook who is believed to have infected between 51 and 122 people with typhoid fever. The infections caused three confirmed deaths, with unconfirmed estimates of as many as 50.
Typhoid fever causes 11 million infections and more than 100,000 deaths per year, and is most prevalent in south Asia – which accounts for 70% of the global disease burden.
During the American Civil War, 81,360 Union soldiers died of typhoid or dysentery, far more than died of battle wounds. [25] In the late 19th century, the typhoid fever mortality rate in Chicago averaged 65 per 100,000 people a year. The worst year was 1891, when the typhoid death rate was 174 per 100,000 people. [26]
Yes, you can get norovirus twice. “People can get infected with norovirus countless times,” says infectious disease expert Amesh A. Adalja, M.D., a senior scholar at the Johns Hopkins Center ...
The chlorination of public drinking water led to the sharp reduction of typhoid in developed nations. [8] In typhoid-endemic countries, Typhoid vaccines have been shown to prevent 40 to 90% of cases during the first two years, [ 9 ] and may have some effect for up to seven years.
For instance, some people follow a schedule that includes 20-minute naps every four hours for a total of two hours of daily sleep. Others sleep for 90 minutes three times a day, for a total of ...
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