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Hidradenitis suppurativa (HS), sometimes known as acne inversa or Verneuil's disease, is a long-term dermatological condition characterized by the occurrence of inflamed and swollen lumps. [ 2 ] [ 3 ] These are typically painful and break open, releasing fluid or pus . [ 3 ]
Hidradenitis suppurativa is a chronic cutaneous condition originally thought to be primarily characterized by suppurative inflammation of the apocrine sweat glands. [ 3 ] : 710 Recent evidence supports that the primary event is follicular hyperkeratosis and obstruction, [ 4 ] but the term hidradenitis supperativa has continued to be used in ...
Hidradenitis suppurativa is a chronic inflammatory skin condition that impacts up to two percent of people in the U.S. (That's roughly 6.5 million people.) But while the condition can be ...
Povorcitinib is an investigational new drug that is being evaluated for the treatment of the skin conditions hidradenitis suppurativa [1] [2] and chronic prurigo. [ 3 ] [ 4 ] It is a JAK1 inhibitor. [ 5 ]
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A TNF inhibitor is a pharmaceutical drug that suppresses the physiologic response to tumor necrosis factor (TNF), which is part of the inflammatory response.TNF is involved in autoimmune and immune-mediated disorders such as rheumatoid arthritis, ankylosing spondylitis, inflammatory bowel disease, psoriasis, hidradenitis suppurativa and refractory asthma, so TNF inhibitors may be used in their ...
They may become inflamed and heal with scarring, like acne nodules (see nodulocystic acne and hidradenitis suppurativa). On inflammation they can become incredibly painful and reach sizes between 4-6cm in diameter.
Known androgen-dependent conditions include acne, [1] seborrhea, [2] [3] [4] androgenic alopecia, [5] hirsutism, [6] hidradenitis suppurativa, [7] precocious puberty in boys, [8] hypersexuality, [9] paraphilias, [10] benign prostatic hyperplasia (BPH), [11] prostate cancer, [12] and hyperandrogenism in women such as in polycystic ovary syndrome ...
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