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24–48 hours following presentation with mild viral symptoms [2] Causes: Exposure to pathogens following splenectomy or asplenia: Risk factors: Splenectomy in the past 2–3 years, removal of spleen for hematological reasons, being under the age of 2 [2] Prognosis: Almost invariably fatal without treatment [2]
In one series of 59 patients, mortality amounted to 5%. [3] Complications include a ruptured spleen, bleeding, an abscess of the spleen (for example, if the underlying cause is infective endocarditis) or pseudocyst formation. Splenectomy may be warranted for persistent pseudocysts due to the high risk of subsequent rupture. [4]
For long-term treatment of congenital pyruvate kinase (PK) deficiency; Those who have a severe version of the hereditary blood disorder Spherocytosis. During surgical resection of a pancreatic cancer; The classical cause of traumatic damage to the spleen is a blow to the abdomen during a sporting event.
The most frequent cause of autosplenectomy is sickle cell anemia [10] which causes progressive splenic hypofunction over time. Increased deoxygenation causes sickling of red blood cells, which adhere to the spleen wall and splenic macrophages causing ischemia . [ 2 ]
Rescue treatment involves acute symptomatic control with medication. [4] Recommendations for rescue therapy of migraine include: (1) migraine-specific agents such as triptans, CGRP antagonists, or ditans for patients with severe headaches or for headaches that respond poorly to analgesics, (2) non-oral (typically nasal or injection) route of administration for patients with vomiting, (3) avoid ...
According to the Mayo Clinic, when a spleen is removed, other organs generally take over its functions, but along with the higher risk of serious infections, a patient without a spleen has ...
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