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Neprilysin (/ ˌ n ɛ p r ɪ ˈ l aɪ s ɪ n /; also known as membrane metallo-endopeptidase (MME), neutral endopeptidase (NEP), cluster of differentiation 10 (CD10) and common acute lymphoblastic leukemia antigen (CALLA)) is an enzyme that in humans is encoded by the MME gene.
CD10: Renal cell carcinoma: CD15: Hodgkin's disease: CD20: Primary cutaneous marginal zone lymphoma Primary cutaneous follicular lymphoma Diffuse large B-cell lymphoma leg type: CD30 (Ki-1) Lymphomatoid papulosis Primary cutaneous anaplastic large cell lymphoma Eosinophilic ulcer of the oral mucosa Hodgkin's disease: CD31: Endothelial cell ...
Cases of non-CLL/SLL MBL in which the monoclonal B cells do not express CD5, CD23, CD10, or CD103 but strongly express CD79B and light chain Ig have been tentatively designated as having monoclonal B-cell lymphocytosis of the marginal zone (i.e. CBL-MZ). This term is used because normal marginal zone B-cell lymphocytes express these markers.
CD10: a type II transmembrane protein found on pre-B cells, germinal-center B cells, some neutrophils, kidney cells, T-cell precursors, and epithelial cells that acts as a zinc metalloprotease cleaving peptide bonds on the amino side of hydrophobic amino acids; expressed in acute lymphocytic leukemia and follicular-center-cell lymphomas. CD11a
CD10 positive cells are metalloproteinase which activate or deactivate peptides through proteolytic cleavage. [ 9 ] An official diagnosis of follicular hyperplasia might include imagining such as a PET scan and a tissue biopsy , depending on the clinical location and also the location of lymphadenopathy . [ 6 ]
T-cell/histiocyte-rich large B-cell lymphoma (THRLBCL) is a malignancy of B cells.B-cells are lymphocytes that normally function in the humoral immunity component of the adaptive immune system by secreting antibodies that, for example, bind to and neutralize invasive pathogens.
The CD nomenclature was proposed and established in the 1st International Workshop and Conference on Human Leukocyte Differentiation Antigens (HLDA), held in Paris in 1982. [4] [5] This system was intended for the classification of the many monoclonal antibodies (mAbs) generated by different laboratories around the world against epitopes on the surface molecules of leukocytes (white blood cells).
Duodenal-type follicular lymphoma (DFL) is a form of lymphoma in which certain lymphocyte types, the B-cell-derived centrocytes and centroblasts, form lymph node follicle-like structures principally in the duodenum and other parts of the small intestine.