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  2. Isolated primary immunoglobulin M deficiency - Wikipedia

    en.wikipedia.org/wiki/Isolated_primary...

    The cause of selective IgM deficiency remains unclear, although various mechanisms have been proposed, such as an increase in regulatory T cell functions, defective T helper cell functions and impaired terminal differentiation of B lymphocytes into IgM-secreting cells among others. [2]

  3. Hypogammaglobulinemia - Wikipedia

    en.wikipedia.org/wiki/Hypogammaglobulinemia

    Screening of immunoglobulin levels in relatives of CVID and IgA patients finds a familial inheritance rate of 10% to 20%. In cases where a carrier of such a mutation would like to have children, preimplantation genetic diagnosis (PGD) has been offered. [2] PGD is defined as the testing of pre-implantation stage embryos or oocytes for genetic ...

  4. Common variable immunodeficiency - Wikipedia

    en.wikipedia.org/wiki/Common_variable...

    Common variable immunodeficiency (CVID) is an inborn immune disorder characterized by recurrent infections and low antibody levels, specifically in immunoglobulin (Ig) types IgG, IgM, and IgA. [2] Symptoms generally include high susceptibility to pathogens, chronic lung disease, as well as inflammation and infection of the gastrointestinal ...

  5. Low levels of biomarker could predict heart disease risk in ...

    www.aol.com/low-levels-biomarker-could-predict...

    The women with the highest levels of IgM anti-PC had a 73% lower risk of CVD than those in the group with the lowest levels. The reduction was most evident in the risk of ischemic heart disease ...

  6. Immunoglobulin M - Wikipedia

    en.wikipedia.org/wiki/Immunoglobulin_M

    Immunoglobulin M (IgM) is the largest of several isotypes of antibodies (also known as immunoglobulin) that are produced by vertebrates.IgM is the first antibody to appear in the response to initial exposure to an antigen; [1] [2] causing it to also be called an acute phase antibody.

  7. Humoral immune deficiency - Wikipedia

    en.wikipedia.org/wiki/Humoral_immune_deficiency

    B cells low but present, but with reduction in 2 or more isotypes (usually IgG & IgA, sometimes IgM): common variable immunodeficiency (CVID), ICOS deficiency, CD19 deficiency, TACI (TNFRSF13B) deficiency, BAFF receptor deficiency. Normal numbers of B cells with decreased IgG and IgA and increased IgM: Hyper-IgM syndromes

  8. Low calcium, magnesium levels tied to poorer cognitive ... - AOL

    www.aol.com/low-calcium-magnesium-levels-tied...

    Older adults with calcium and magnesium deficiencies also had poorer cognitive performance compared to peers with adequate micronutrient levels, a recent study has found. Low calcium, magnesium ...

  9. Primary immunodeficiency - Wikipedia

    en.wikipedia.org/wiki/Primary_immunodeficiency

    The basic tests performed when an immunodeficiency is suspected should include a full blood count (including accurate lymphocyte and granulocyte counts) and immunoglobulin levels (the three most important types of antibodies: IgG, IgA and IgM). [6] [5] Other tests are performed depending on the suspected disorder: [5] [6]

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