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Cholesteatoma is a destructive and expanding growth consisting of keratinizing squamous epithelium in the middle ear and/or mastoid process. [1] [2] Cholesteatomas are not cancerous as the name may suggest, but can cause significant problems because of their erosive and expansile properties.
Whilst hearing loss is a common symptom in many diseases of the ear, for example in otosclerosis (abnormal bone growth in the ear), [3] the white, chalky patches on the tympanic membrane are fairly characteristic of tympanosclerosis. Cholesteatoma is similar in appearance but the whiteness is behind the tympanic membrane, rather than inside.
Ceruminous adenocarcinoma is a malignant neoplasm derived from ceruminous glands of the external auditory canal.This tumor is rare, with several names used in the past. [3] [4] Synonyms have included cylindroma, ceruminoma, ceruminous adenocarcinoma, not otherwise specified (NOS), ceruminous adenoid cystic carcinoma (ACC), [1] [2] and ceruminous mucoepidermoid carcinoma.
A hematoxylin and eosin stained intermediate power showing an infiltrating tumor with glandular and neuroendocrine features in a neuroendocrine adenoma of the middle ear. At the time of surgery, the tumor tends to peel away from the adjacent bones, although not the ossicles. It is usually fragmented, soft, rubbery and white to gray-tan.
Lung cancer in non-smokers is increasing “on a relative basis,” as the number of people who smoke has decreased, says Dr. William Dahut, chief scientific officer at the American Cancer Society.
A ceruminous adenoma is a benign glandular neoplasm which arises from the ceruminous glands located within the external auditory canal. These glands are found within the outer one third to one half of the external auditory canal, more common along the posterior surface; therefore, the tumor develops within a very specific location.
After treatment with white button mushroom extract in mice and patients with prostate cancer, scientists discovered a decline in the amount of immune-suppressing cells in tumors.
A soft-tissue sarcoma (STS) is a malignant tumor, a type of cancer, that develops in soft tissue. [1] A soft-tissue sarcoma is often a painless mass that grows slowly over months or years. They may be superficial or deep-seated. Any such unexplained mass must be diagnosed by biopsy. [2]