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To understand the rationale behind this relation, think of A as the length/amount of time spent in the susceptible group (assuming an individual is susceptible before contracting the disease and immune afterwards) and L as the total length of time spent in the population. It thus follows that the proportion of time spent as a susceptible is A/L ...
Viral host tropism is determined by a combination of susceptibility and permissiveness: a host cell must be both permissive (allow viral replication) and susceptible (possess the receptor complement needed for viral entry) for a virus to establish infection.
A virus can enter a susceptible cell, but it may or may not be able to replicate. A virus may only replicate in a permissive cell. Viral replication will therefore occur in a susceptible cell which is also a permissive cell that 1) facilitates entry (susceptibility) and 2) supports intracellular replication (permissive cell).
Control mechanisms include the suppression of intrinsic cell defenses, suppression of cell signaling and suppression of host cellular transcription and translation. Often, these cytotoxic effects lead to the death and decline of a cell infected by a virus. A cell is classified as susceptible to a virus if the virus is able to enter the cell.
Permissive may refer to: . Permissive society, a liberalization of social norms in a society.; Permissive software license, a free-software license.; Permissive cell or permissive host, a cell which allows a virus to circumvent its defenses and replicate.
In epidemiology, particularly in the discussion of infectious disease dynamics (mathematical modeling of disease spread), the infectious period is the time interval during which a host (individual or patient) is infectious, i.e. capable of directly or indirectly transmitting pathogenic infectious agents or pathogens to another susceptible host ...
To give a few examples, Morbillivirus is transmitted from an infected human host to a susceptible host as they are transmitted by respiration through airborne transmission. Campylobacter (campylobacteriosis) is a common bacterial infection that is spread from human or non-human reservoirs by vehicles such as contaminated food and water.
In epidemiology, particularly in the discussion of infectious disease dynamics (modeling), the latent period (also known as the latency period or the pre-infectious period) is the time interval between when an individual or host is infected by a pathogen and when that individual becomes infectious, i.e. capable of transmitting pathogens to ...