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The formation of phenyl-hydroxy bromazolam was catalysed by CYP2B6, CYP2C19, and CYP3A4. 4-hydroxy bromazolam, as well as α-hydroxy bromazolam, were formed by CYP2B6, CYP2C19, CYP3A4, and CYP3A5. Additionally, CYP2C9 was found to catalyse the formation of α-hydroxy bromazolam as well. α-4-dihydroxy bromazolam was only found in incubations ...
Side effects. Topical decongestants should not be used for longer than a week as prolonged use may result in rhinitis medicamentosa (rebound nasal congestion). [13] Common side effects for oral decongestants include insomnia, hypertension (elevated blood pressure), and difficulty in urination. [12]
The tables below contain a sample list of benzodiazepines and benzodiazepine analogs that are commonly prescribed, with their basic pharmacological characteristics, such as half-life and equivalent doses to other benzodiazepines, also listed, along with their trade names and primary uses.
The ultrashort 1hr half-life gives Zaleplon a unique advantage over other hypnotics because of its lack of next-day residual effects on driving and other performance-related skills. [ 35 ] [ 36 ] Zaleplon is primarily metabolised by aldehyde oxidase into 5-oxozaleplon, and its half-life may be affected by substances which inhibit or induce ...
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Some common side effects include burning and stinging sensations. [10] [11] [21] [25] Colour change of the skin, bump formation on the skin and additional hair growth could also occur. [11] [19] Consult a doctor if these side effects persist or become worse. [11] [19] Some severe side effects are severe rash, swelling of the skin, and skin ...
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Berotralstat, sold under the brand name Orladeyo, is a medication used to prevent attacks of hereditary angioedema (HAE) in people aged twelve years and older. [3] [5] [7] [8] [4]