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Prolactin (PRL), also known as lactotropin and mammotropin, is a protein best known for its role in enabling mammals to produce milk. It is influential in over 300 separate processes in various vertebrates, including humans. [5] Prolactin is secreted from the pituitary gland in response to eating, mating, estrogen treatment, ovulation and ...
A prolactin cell (also known as a lactotropic cell, epsilon acidophil, lactotrope, lactotroph, mammatroph, mammotroph) is a cell in the anterior pituitary which produces prolactin (a peptide hormone) in response to hormonal signals including dopamine (which is inhibitory), thyrotropin-releasing hormone and estrogen (especially during pregnancy), which are stimulatory.
Unlike most tropic hormones released by the anterior pituitary gland, prolactin secretion is primarily regulated by hypothalamic inhibition rather than by negative feedback from peripheral hormones. Prolactin also self-regulates through a counter-current flow in the hypophyseal pituitary portal system, which triggers the release of hypothalamic ...
The following is a list of hormones found in Humans. Spelling is not uniform for many hormones. For example, current North American and international usage uses [citation needed] estrogen and gonadotropin, while British usage retains the Greek digraph in oestrogen and favours the earlier spelling gonadotrophin.
This hormone is closely associated with prolactin and appears to be instrumental in breast, nipple, and areola growth before birth. Follicle stimulating hormone (FSH), luteinizing hormone (LH), and human chorionic gonadotropin (hCG), through control of estrogen and progesterone production, and also, by extension, prolactin and growth hormone ...
Estrogen and progesterone cause the secretion of high levels of prolactin from the anterior pituitary, [32] [33] which reach levels as high as 20 times greater than normal menstrual cycle levels. [31] IGF-1 and IGF-2 levels also increase dramatically during pregnancy, due to secretion of placental growth hormone (PGH). [34]
Prolactin and insulin-like growth factor binding protein are two examples of the hormones and growth factors that relaxin can stimulate the secretion of. [21] Preprorelaxin is the collective term for the signal peptide , B chain, C peptide, and A chain found in the coding area of human relaxin genes. [ 22 ]
The hormone prolactin has a key role in lactation and breast development in the human body and it is also a functional component of homeostasis. [15] It has varying originations including the central nervous system (CNS), the immune system, mammary glands, and uterus.