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The respiratory tract antimicrobial defense system is a layered defense mechanism which relies on components of both the innate and adaptive immune systems to protect the lungs and the rest of the respiratory tract against inhaled microorganisms.
The former affords a higher level of protection, but is less comfortable. [2] Tight-fitting PAPRs require a fit test in hazardous workplace environments, while loose-fitting PAPR users can avoid OSHA fit test requirements in certain hazardous workplace environments (see OSHA's respirator assigned protection factors for more information).
The respiratory system (also respiratory apparatus, ventilatory system) is a biological system consisting of specific organs and structures used for gas exchange in animals and plants. The anatomy and physiology that make this happen varies greatly, depending on the size of the organism, the environment in which it lives and its evolutionary ...
Mucociliary clearance (MCC), mucociliary transport, or the mucociliary escalator describes the self-clearing mechanism of the airways in the respiratory system. [1] It is one of the two protective processes for the lungs in removing inhaled particles including pathogens before they can reach the delicate tissue of the lungs.
Mucosal immunology is the study of immune system responses that occur at mucosal membranes of the intestines, the urogenital tract, and the respiratory system. [1] The mucous membranes are in constant contact with microorganisms , food, and inhaled antigens . [ 2 ]
SCBA is intended to be personal protective equipment, but its use is not without cost. The weight of the unit and work of breathing affect the work capacity and agility of the wearer, and the full-face mask, while protecting the face and eyes from heat, smoke, and toxic gases, also reduces peripheral vision and awareness of the surroundings.
The fitting characteristic of a respirator is the ability of the mask to separate a worker's respiratory system from ambient air. This is achieved by tightly pressing the mask flush against the face (without gaps) to ensure an efficient seal on the mask perimeter.
The lungs possess several characteristics which protect against infection. The respiratory tract is lined by respiratory epithelium or respiratory mucosa, with hair-like projections called cilia that beat rhythmically and carry mucus. This mucociliary clearance is an important defence system against air-borne infection. [34]