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The pancreatic islets or islets of Langerhans are the regions of the pancreas that contain its endocrine (hormone-producing) cells, discovered in 1869 by German pathological anatomist Paul Langerhans. [1] The pancreatic islets constitute 1–2% of the pancreas volume and receive 10–15% of its blood flow. [2] [3] The pancreatic islets are ...
Beta cells (β-cells) are specialized endocrine cells located within the pancreatic islets of Langerhans responsible for the production and release of insulin and amylin. [1] Constituting ~50–70% of cells in human islets, beta cells play a vital role in maintaining blood glucose levels. [2] Problems with beta cells can lead to disorders such ...
The tissues with an endocrine role within the pancreas exist as clusters of cells called pancreatic islets (also called islets of Langerhans) that are distributed throughout the pancreas. [9] Pancreatic islets contain alpha cells, beta cells, and delta cells, each of which releases a different hormone.
Islets of Langerhans. Alpha cell; Beta cell; PP cell (F cell, gamma cell) Delta cell; Epsilon cell; Pharyngeal pouch. Thyroid gland Follicular cell; Parafollicular ...
Pancreatic polypeptide cells (PP cells), or formerly as gamma cells (γ-cells), or F cells, are cells in the pancreatic islets (Islets of Langerhans) of the pancreas.Their main role is to help synthesize and regulate the release of pancreatic polypeptide (PP), after which they have been named.
At first, there was a lot of controversy about what the Islets were made of and what they did. [3] It appeared that all of the cells were the same within the Islet, but were histologically distinct from acini cells. [3] Laguesse discovered that the cells within the Islets of Langerhans contained granules that distinguished them from acini cells ...
Epsilon cells (ε-cells) are one of the five types of endocrine cells found in regions of the pancreas called Islets of Langerhans. [1] Epsilon cells produce the hormone ghrelin that induces hunger. They were first discovered in mice. In humans, these cells compose less than 1% of all islet cells.
Langerhans cell is represented by a yellow oval; blue arrows correspond to is_a relations, and orange arrows correspond to develops_from relations. Only a subset of Langerhans cell parent types are included in the figure. [1] A Langerhans cell (LC) is a tissue-resident macrophage of the skin [2] once thought to be a resident dendritic cell. [3]