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Various approaches to approve effectiveness and limit side effects are being investigated, including radiosensitising drugs, fractionation regimes and new radionuclides. [16] Alpha emitters, which have much shorter ranges in tissue (limiting the effect on nearby healthy tissue), such as bismuth-213 or actinium-225 labelled DOTATOC are of ...
Targeted alpha-particle therapy (or TAT) is an in-development method of targeted radionuclide therapy of various cancers. It employs radioactive substances which undergo alpha decay to treat diseased tissue at close proximity. [1] It has the potential to provide highly targeted treatment, especially to microscopic tumour cells.
Additionally, theranostic approaches involving radiolabeled therapeutic agents, known as radiotheranostics, combine the therapeutic effects of radiation with diagnostic capabilities. Radiotheranostics, including Peptide receptor radionuclide therapy (PRRT), hold promise for targeted radiotherapy, enabling precise tumor targeting and dose ...
Side effects are dose-dependent; for example, higher doses of head and neck radiation can be associated with cardiovascular complications, thyroid dysfunction, and pituitary axis dysfunction. [15] Modern radiation therapy aims to reduce side effects to a minimum and to help the patient understand and deal with side effects that are unavoidable.
The latest research on dogs in the Chernobyl Exclusion Zone defies what many scientists suspected Genetic differences in Chernobyl dogs may not be down to radiation, new study suggests Skip to ...
Radiation-induced mutations may not be the reason for the genetic differences between dog populations living near the Chernobyl nuclear power plant, according to a new study.
The second, Project Six, started in 1957 to investigate the effects of ingesting low levels of radionuclides. [2] The facility, which became known as the Laboratory for Energy-Related Health Research (LEHR), occupied 15 acres of land. [2] Both projects had the capacity to hold up to five hundred dogs in two-dog pens. [2]
External beam radiation therapy (EBRT) is a form of radiotherapy that utilizes a high-energy collimated beam of ionizing radiation, from a source outside the body, to target and kill cancer cells. The radiotherapy beam is composed of particles, which are focussed in a particular direction of travel using collimators [ 1 ] .