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Although the injection drugs are shown to be safe for children with precocious puberty, they may cause rare side effects like the risk of reactions at the injection site or weakened bones if given ...
Additionally, by halting the rapid growth spurts of puberty, these medications provide more time for growth in stature, particularly beneficial for children diagnosed with idiopathic short stature or central precocious puberty. Common short-term side effects may include injection site reactions, headaches, mood swings, changes in weight or ...
A study investigating the effects of puberty blockers on reproductive health showed no significant difference in the number of irregular menstrual cycles, pregnancies, or pregnancy outcomes between women who received treatment for precocious puberty and those who opted out of treatment. [45]
A by mouth formulation of leuprorelin is under development for the treatment of endometriosis. [61] It was also under development for the treatment of precocious puberty, prostate cancer, and uterine fibroids, but development for these uses was discontinued. [61] The formulation has the tentative brand name Ovarest. [61]
One red flag to look out for is if precocious puberty occurs too early, such as around 4 or 6 years old. While extremely rare, this should be brought to the attention of your child’s ...
Van Wyk and Grumbach syndrome is a medical condition defined by a combination of hypothyroidism, precocious puberty (with delayed bone age and lack of pubic hair), and ovarian cysts in pre- and post-pubertal girls or macroorchidism (unusually large testes) in boys. [1]
Starting puberty significantly early — younger than age 8 in girls, 9 in boys — may have health effects lasting into adulthood, including higher risks of breast cancer, diabetes and heart disease.
The goals of short-term hormone therapy are to induce the beginning of sexual development and induce a growth spurt, but it should be limited to children with severe distress or anxiety secondary to their delayed puberty. [2] [7] Bone age must be monitored frequently to prevent precocious closure of the bone plates, thereby stunting growth. [7]
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