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As of 2018, the best available evidence favors low-dose thiazide diuretics as the first-line treatment of choice for high blood pressure when drugs are necessary. [5] Although clinical evidence shows calcium channel blockers and thiazide-type diuretics are preferred first-line treatments for most people (from both efficacy and cost points of ...
Amiodarone is an antiarrhythmic medication used to treat and prevent a number of types of cardiac dysrhythmias. [4] This includes ventricular tachycardia, ventricular fibrillation, and wide complex tachycardia, atrial fibrillation, and paroxysmal supraventricular tachycardia. [4]
Compared with certain other L-type calcium channel blockers (for example those of the phenylalkylamine class such as verapamil) that have significant action at the heart, the dihydropyridine calcium channel blockers lower blood pressure mainly by relaxing the smooth muscle of the blood vessel walls. [3]
Amlodipine/olmesartan, sold under the brand name Azor, among others is a fixed-dose combination medication used to treat high blood pressure. [5] It contains amlodipine, as the besilate, a dihydropyridine calcium channel blocker, and olmesartan medoxomil, an angiotensin II receptor blocker.
Lifestyle changes and medications can lower blood pressure and decrease the risk of health complications. [8] Lifestyle changes include weight loss, physical exercise, decreased salt intake, reducing alcohol intake, and a healthy diet. [5] If lifestyle changes are not sufficient, blood pressure medications are used. [8]
By increasing cAMP levels, these medications cause the smooth muscles to relax. [34] This relaxation has a significant benefit in our blood vessels as it leads to vasodilation, which means the blood vessels widen. [34] [35] Vasodilation helps to reduce resistance against blood flow, allowing for better circulation throughout the body. [36]
Amiodarone induced thyrotoxicosis (AIT) is a form of hyperthyroidism due to treatment with antiarrhythmic drug, amiodarone. Amiodarone induced thyroid dysfunction more commonly results in hypothyroidism , estimated to occur in 6-32% of patients, whereas hyperthyroidism from amiodarone use is estimated at 1-12%. [ 1 ]
Medications recommended in the ACLS protocol include epinephrine, amiodarone, and lidocaine. [9] The timing and administration of these medications depends on the underlying arrhythmia of the arrest. Epinephrine acts on the alpha-1 receptor, which in turn increases the blood flow that supplies the heart. [ 105 ]