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Dengue vaccine is a vaccine used to prevent dengue fever in humans. [9] Development of dengue vaccines began in the 1920s but was hindered by the need to create immunity against all four dengue serotypes. [10] As of 2023, there are two commercially available vaccines, sold under the brand names Dengvaxia and Qdenga. [11] [12]
Dengue is spread by several species of female mosquitoes of the Aedes genus, principally Aedes aegypti. [1] Infection can be prevented by mosquito elimination and the prevention of bites. [12] Two types of dengue vaccine have been approved and are commercially available.
In May 2024, TAK-003 became the second dengue vaccine to be prequalified by the World Health Organization (WHO). [51] This live-attenuated vaccine, developed by Takeda is similar to the Dengvaxia vaccine in the fact that it contains a weakened version of the four variants of dengue virus. The difference between the two vaccines is the TAK-003 ...
The Advisory Committee on Immunization Practices recommends the dengue vaccine, Dengvaxia, for children 9–16 years old with prior laboratory-confirmed dengue virus infection and living in areas ...
A risk assessment report published Tuesday by the Pan-American Health Organization noted that the “lack of robust dengue surveillance and management systems raises concerns about potential ...
Dengue virus (DENV) is the cause of dengue fever.It is a mosquito-borne, single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. [1] [2] Four serotypes of the virus have been found, and a reported fifth has yet to be confirmed, [3] [4] [5] all of which can cause the full spectrum of disease. [1]
A Spanish laboratory is breeding and sterilising thousands of tiger mosquitoes to fight dengue fever and other diseases as climate change encourages the invasive species to spread across Europe.
It is based on a weakened combination of the yellow fever virus and each of the four dengue serotypes. [30] [52] Two studies of a vaccine found it was 60% effective and prevented more than 80 to 90% of severe cases. [53] [54] This is less than wished for by some. [50] There are ongoing programs working on a dengue vaccine to cover all four ...