Ads
related to: vascular smooth muscle cells atherosclerosis diseasewexnermedical.osu.edu has been visited by 10K+ users in the past month
- Treatment Options
Coronary Catheter
Surgical Treatment
- Symptoms & Causes
Lifestyle Changes
Heart Disease Prevention
- Should I see a Heart Doc
Talk to your doc about your heart
and learn what to ask
- Patient Testimonials
Hear from our patients
about their Ohio State experience
- Treatment Options
Search results
Results from the WOW.Com Content Network
Calcification forms among vascular smooth muscle cells of the surrounding muscular layer, specifically in the muscle cells adjacent to atheromas and on the surface of atheroma plaques and tissue. [70] In time, as cells die, this leads to extracellular calcium deposits between the muscular wall and outer portion of the atheromatous plaques.
Lesions reflect leakage of plasma components across vascular endothelium and excessive extracellular matrix production by smooth muscle cells, usually secondary to hypertension. [ 11 ] Hyaline arteriolosclerosis is a major morphologic characteristic of benign nephrosclerosis , in which the arteriolar narrowing causes diffuse impairment of renal ...
The main endogenous agonist of these cell receptors is norepinephrine (NE). The adrenergic receptors exert opposite physiologic effects in the vascular smooth muscle under activation: alpha-1 receptors. Under NE binding alpha-1 receptors cause vasoconstriction (contraction of the vascular smooth muscle cells decreasing the diameter of the ...
Nitric oxide (NO) suppresses platelet aggregation, inflammation, oxidative stress, vascular smooth muscle cell migration and proliferation, and leukocyte adhesion. [6] A feature of endothelial dysfunction is the inability of arteries and arterioles to dilate fully in response to an appropriate stimulus, such as exogenous nitroglycerine , [ 5 ...
Atheroma is the pathological basis for the disease entity atherosclerosis, ... typically within smooth muscle cells of the arterial ... and noted 22 vascular events ...
Hydroxyapatite is secreted in vesicles that bleb out from vascular smooth muscle cells or pericytes in the arterial wall. [3] The mechanism of vascular calcification is not fully understood, but probably involves a phenotypic change in the vascular smooth muscle cells in the wall with activation of bone-forming programs.
Atherosclerosis is a developmental disease in the large arteries, defined by the accumulation of lipids, macrophages and fibrous materials in the intima. [1] When the endothelial cell of blood vessel is damaged, it loses the ability to regulate itself. [1] It results in inflammation as the macrophages irrupt the vessel wall. [1]
The chronic endothelial injury hypothesis is one of two major mechanisms postulated to explain the underlying cause of atherosclerosis and coronary heart disease (CHD), the other being the lipid hypothesis. Although an ongoing debate involving connection between dietary lipids and CHD sometimes portrays the two hypotheses as being opposed, they ...
Ads
related to: vascular smooth muscle cells atherosclerosis diseasewexnermedical.osu.edu has been visited by 10K+ users in the past month