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This is a list of the largest known epidemics and pandemics caused by an infectious disease in humans. Widespread non-communicable diseases such as cardiovascular disease and cancer are not included. An epidemic is the rapid spread of disease to a large number of people in a given population within a short period of time; in meningococcal ...
Plague is considered to be endemic in 26 countries around the world, with most cases found in remote areas of Africa. [68] The three most endemic countries are Madagascar, the Democratic Republic of the Congo and Peru. [69] Outbreaks with dozens of deaths occurred in Madagascar in 2014 and 2017, in India in 1994, and Congo in 2006.
Human infectious diseases may be characterized by their case fatality rate (CFR), the proportion of people diagnosed with a disease who die from it (cf. mortality rate).It should not be confused with the infection fatality rate (IFR), the estimated proportion of people infected by a disease-causing agent, including asymptomatic and undiagnosed infections, who die from the disease.
25,000,000 – 50,000,000 (estimated) The Black Death was a bubonic plague pandemic occurring in Europe from 1346 to 1353. It was one of the most fatal pandemics in human history; as many as 50 million people [2] perished, perhaps 50% of Europe's 14th century population. [3] The disease is caused by the bacterium Yersinia pestis and spread by ...
Plague (disease) Yersinia pestis seen at 200× magnification with a fluorescent label. Plague is an infectious disease caused by the bacterium Yersinia pestis. [2] Symptoms include fever, weakness and headache. [1] Usually this begins one to seven days after exposure. [2] There are three forms of plague, each affecting a different part of the ...
Great Plague of Marseille. The Great Plague of Marseille, also known as the Plague of Provence, was the last major outbreak of bubonic plague in Western Europe. Arriving in Marseille, France, in 1720, the disease killed over 100,000 people: 50,000 in the city during the next two years and another 50,000 to the north in surrounding provinces and ...
The second plague pandemic was a major series of epidemics of plague that started with the Black Death, which reached medieval Europe in 1346 and killed up to half of the population of Eurasia in the next four years. It followed the first plague pandemic that began in the 6th century with the Plague of Justinian, but had ended in the 8th century.
The first plague pandemic was the first historically recorded Old World pandemic of plague, the contagious disease caused by the bacterium Yersinia pestis. Also called the early medieval pandemic, it began with the Plague of Justinian in 541 and continued until 750 or 767. At least fifteen to eighteen major waves of plague following the ...