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Piloerection (goose bumps), the physical part of frisson. Frisson (UK: / ˈ f r iː s ɒ n / FREE-son, US: / f r iː ˈ s oʊ n / free-SOHN [1] [2] French:; French for "shiver"), also known as aesthetic chills or psychogenic shivers, is a psychophysiological response to rewarding stimuli (including music, films, stories, people, photos, and rituals [3]) that often induces a pleasurable or ...
Cold sensitivity or cold intolerance is unusual discomfort felt by some people when in a cool environment. [ 1 ] Cold sensitivity may be a symptom of hypothyroidism , anemia , low body weight, iron deficiency , vitamin B 12 deficiency , fevers , fibromyalgia or vasoconstriction . [ 2 ]
Allodynia is a condition in which pain is caused by a stimulus that does not normally elicit pain. [1] For example, sunburn can cause temporary allodynia, so that usually painless stimuli, such as wearing clothing or running cold or warm water over it, can be very painful.
Chills is a feeling of coldness occurring during a high fever, but sometimes is also a common symptom which occurs alone in specific people. It occurs during fever due to the release of cytokines and prostaglandins as part of the inflammatory response , which increases the set point for body temperature in the hypothalamus .
A cold-stimulus headache, colloquially known as an ice-cream headache or brain freeze, is a form of brief pain or headache commonly associated with consumption (particularly quick consumption) of cold beverages or foods such as ice cream, popsicles, and snow cones.
Frostbite is a skin injury that occurs when someone is exposed to extremely low temperatures, causing the freezing of the skin or other tissues, [1] commonly affecting the fingers, toes, nose, ears, cheeks and chin areas. [6]
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TRPM8 is an ion channel: upon activation, it allows the entry of Na + and Ca 2+ ions into the cell, which leads to depolarization and the generation of an action potential. . The signal is conducted from primary afferents (type C- and A-delta) eventually leading to the sensation of cold and cold p