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  2. AL amyloidosis - Wikipedia

    en.wikipedia.org/wiki/AL_amyloidosis

    Median survival for patients diagnosed with AL amyloidosis was 13 months in the early 1990s, but had improved to about 40 months a decade later with 5 year survival rates also increasing from 15% in the 1980s to 48% in the mid 2010s . [17] [4] Heart involvement is associated with a worse prognosis. [18]

  3. Amyloidosis - Wikipedia

    en.wikipedia.org/wiki/Amyloidosis

    Survival diminishes with increasing stage, but recent advancements in treatments have improved median survival rates for stages I, II, and III, to 91.2, 60, and 7 months respectively. [45] Outcomes in a person with AA amyloidosis depend on the underlying disease, organ(s) affected, and correlate with the concentration of serum amyloid A protein ...

  4. Cardiac amyloidosis - Wikipedia

    en.wikipedia.org/wiki/Cardiac_amyloidosis

    Light chain (AL-CM) Prognosis: For light-chain amyloidosis early detection leads to best possibility of therapies prolonging the period of remission. [3] Well treated light chain cardiac amyloidosis has a 4-year survival rate of around 90%. [5] In patients that undergo stem cell transplant the average survival time increases to 10 years. [5]

  5. LECT2 amyloidosis - Wikipedia

    en.wikipedia.org/wiki/Lect2_amyloidosis

    LECT2 Amyloidosis (ALECT2) is a form of amyloidosis caused by the LECT2 protein. It was found to be the third most common (~3% of total) cause of amyloidosis in a set of more than 4,000 individuals studied at the Mayo Clinic; the first and second most common forms the disorder were AL amyloidosis and AA amyloidosis, respectively.

  6. Wild-type transthyretin amyloid - Wikipedia

    en.wikipedia.org/wiki/Wild-Type_Transthyretin...

    Wild-type transthyretin amyloid (WTTA), also known as senile systemic amyloidosis (SSA), [1] is a disease that typically affects the heart and tendons of elderly people. It is caused by the accumulation of a wild-type (that is to say a normal ) protein called transthyretin .

  7. Amyloid cardiomyopathy - Wikipedia

    en.wikipedia.org/wiki/Amyloid_cardiomyopathy

    5-year survival rate of 10% [2] Amyloid cardiomyopathy ( stiff heart syndrome ) [ 5 ] is a condition resulting in the death of part of the myocardium (heart muscle). It is associated with the systemic production and release of many amyloidogenic proteins , especially immunoglobulin light chain or transthyretin (TTR). [ 6 ]

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  9. AA amyloidosis - Wikipedia

    en.wikipedia.org/wiki/AA_amyloidosis

    AA amyloidosis is a form of amyloidosis, a disease characterized by the abnormal deposition of fibers of insoluble protein in the extracellular space of various tissues and organs. In AA amyloidosis, the deposited protein is serum amyloid A protein (SAA), an acute-phase protein which is normally soluble and whose plasma concentration is highest ...

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