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The cells of bacteria (prokaryotes), such as salmonella, differ from those of higher-level organisms , such as fish. Antibiotics are chemicals designed to either kill or inhibit the growth of pathogenic bacteria while exploiting the differences between prokaryotes and eukaryotes in order to make them relatively harmless in higher-level ...
The cephalosporins (and other β-lactams) have the ability to kill bacteria by inhibiting essential steps in the bacterial cell wall synthesis which in the end results in osmotic lysis and death of the bacterial cell. [2] Cephalosporins are widely used antibiotics because of their clinical efficiency and desirable safety profile. [3]
β-Lactam antibiotics are indicated for the prevention and treatment of bacterial infections caused by susceptible organisms. At first, β-lactam antibiotics were mainly active only against gram-positive bacteria, yet the recent development of broad-spectrum β-lactam antibiotics active against various gram-negative organisms has increased their usefulness.
Bacteriophages and their host ranges are extremely specific for certain bacteria, thus, unlike antibiotics, they do not disturb the host organism's intestinal microbiota. [201] Bacteriophages, also known as phages, infect and kill bacteria primarily during lytic cycles.
Edwardsiella tarda is a member of the family Hafniaceae. [1] [2] The bacterium is a facultatively anaerobic, small, motile, gram negative, straight rod with flagella.[1] [2] Infection causes Edwardsiella septicemia (also known as ES, edwardsiellosis, emphysematous putrefactive disease of catfish, fish gangrene, and red disease) in channel catfish, eels, and flounder.
Infection is usually associated either with swimming, preparing sea food, or with keeping or working with aquarium fish. [2] Infections of humans are rare due to the chlorination of water. [ 4 ] The bacteria penetrate the skin through trauma, usually from bites, injuries from fins, and penetration from foreign objects.
Streptococcus iniae is a species of Gram-positive, sphere-shaped bacterium belonging to the genus Streptococcus.Since its isolation from an Amazon freshwater dolphin in the 1970s, S. iniae has emerged as a leading fish pathogen in aquaculture operations worldwide, resulting in over US$100M in annual losses.
Antimicrobial peptides have been demonstrated to kill Gram negative and Gram positive bacteria, [1] enveloped viruses, fungi and even transformed or cancerous cells. [2] Unlike the majority of conventional antibiotics it appears that antimicrobial peptides frequently destabilize biological membranes , can form transmembrane channels , and may ...