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Telmisartan, sold under the brand name Micardis among others, is a medication used to treat high blood pressure and heart failure. [ 3 ] [ 6 ] It is a reasonable initial treatment for high blood pressure. [ 6 ]
More than 260 medications have been reported to cause tinnitus as a side effect. [41] Tinnitus can also occur from the discontinuation of therapeutic doses of benzodiazepines. It can sometimes be a protracted symptom of benzodiazepine withdrawal and may persist for many months. [42] [43] Medications such as bupropion may also cause tinnitus. [44]
Telmisartan is, on the other hand, in part metabolized by glucuronidation and olmesartan is excreted as the unchanged drug. [23] Telmisartan is the only ARB that can cross the blood–brain barrier and can therefore inhibit centrally mediated effects of Ang II, contributing to even better blood pressure control.
The American Tinnitus Association estimates there are roughly 200 health disorders that can generate tinnitus symptoms. Not exactly a small number. Not exactly a small number. Photo: Getty
Losartan, the first ARB. Angiotensin II receptor blockers (ARBs), formally angiotensin II receptor type 1 (AT 1) antagonists, [1] also known as angiotensin receptor blockers, [2] [3] angiotensin II receptor antagonists, or AT 1 receptor antagonists, are a group of pharmaceuticals that bind to and inhibit the angiotensin II receptor type 1 (AT 1) and thereby block the arteriolar contraction and ...
Ototoxicity of gentamicin can be exploited to treat some individuals with Ménière's disease by destroying the inner ear, which stops the vertigo attacks but causes permanent deafness. [19] Due to the effects on mitochondria, certain inherited mitochondrial disorders result in increased sensitivity to the toxic effects of aminoglycosides.
Though the pathophysiology of tinnitus is not known, noise exposure can be a contributing factor, therefore tinnitus can be associated with hearing loss, generated by the cochlea and central nervous system (CNS). High frequency hearing loss causes a high pitched tinnitus and low frequency hearing loss causes a roaring tinnitus. [19] Noise ...
The most common cause of hyperacusis is overexposure to excessively high decibel (sound pressure) levels, which can cause acoustic trauma. [1] An acoustic shock , which can lead to symptoms such as hyperacusis and ear pain, can also occur after exposure to an unexpected moderately loud to loud noise, even if this does not necessarily result in ...
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