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Metoprolol, sold under the brand name Lopressor among others, is a medication used to treat angina and a number of conditions involving an abnormally fast heart rate. [4] It is also used to prevent further heart problems after myocardial infarction and to prevent headaches in those with migraines . [ 4 ]
The β-blockers are an immensely important class of drugs due to their high prevalence of use. The discovery of β-blockers reaches back to more than 100 years ago, when early investigators came up with the idea that catecholamines were binding selectively to receptor-like structures and that this was the cause of their pharmacological actions. [3]
Timolol is a beta blocker medication used either by mouth or as eye drops. [3] [5] As eye drops it is used to treat increased pressure inside the eye such as in ocular hypertension and glaucoma. [3]
Age can affect the choice of medications. Current UK guidelines suggest starting patients over the age of 55 years first on calcium channel blockers or thiazide diuretics. Age and multi-morbidity can affect the choice of medication, the target blood pressure and even whether to treat or not. [61] Anxiety may be improved with the use of beta ...
Note: bid = two times a day, tid = three times a day, d = daily Drug dosages from Drug Lookup, Epocrates Online. Name Equivalent daily dose Start Usual Maximum Benazepril: 10 mg: 10 mg: 20–40 mg: 80 mg Captopril: 50 mg (25 mg bid) 12.5–25 mg bid-tid: 25–50 mg bid-tid: 150 mg/d Enalapril: 5 mg: 5 mg: 10–40 mg: 40 mg Fosinopril: 10 mg: 10 ...
In clinical studies, about 1% of all patients had to discontinue the drug because of these sensations, which occurred on average 40 days after the drug was started. [ 6 ] In a large clinical trial, bradycardia (unusually slow heart rate) occurred in 2% and 5% of patients taking ivabradine at doses of 7.5 and 10 mg respectively (compared to 4.3% ...
The European Medicines Agency reviewed the drug's safety in 2011, which determined that it should not be prescribed in high doses, for periods of more than five days, or given to children below 1 year of age. They suggested its use in older children should be restricted to treating post-chemotherapy or post-surgery nausea and vomiting, and even ...
The evidence supporting this link has been shown in numerous studies over the past ten years. Nationwide studies and meta-analyses of smaller cohort studies have uncovered a correlation between pre-existing inflammatory conditions such as type 1 diabetes , rheumatoid arthritis (RA), or hepatitis , and an increased risk of depression.
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