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Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [4] [8] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon. [9] It is unclear if it is effective for treating sexual dysfunction in females. [8]
Generic sildenafil (and brand-name Viagra) is a medication for the treatment of ED, Raynaud’s phenomenon, and pulmonary arterial hypertension. To understand how Viagra works, we need to look at ...
Life-threatening problems can result when drug interactions between your daily medications cause side effects, and nowhere might that be more clear than with Viagra and high blood pressure.
Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.
Some drug interactions with other medications can undermine Viagra. Viagra side effects may affect your ability to perform, though most are mild and temporary. All (ED) medications work best when ...
Sildenafil is a prototype of PDE5 inhibitors that Pfizer launched as Viagra. It was approved by the Food and Drug Administration (FDA) in 1998 as the first oral medicine for erectile dysfunction. Later, in the year 2005, it was approved for the treatment of pulmonary arterial hypertension. [2] Vardenafil and tadalafil were discovered in 1990 ...
The U.S. Food and Drug Administration (FDA) has approved several medications for the treatment of ED, including: Sildenafil (the active ingredient in Viagra or generic versions of Viagra ...
Some authors recommend the use of sildenafil by mouth to replace the injectable drugs in cases of contraindications, although the efficacy of such medication is controversial. [ 45 ] Before the injection of the chosen drug, the flow pattern is monophasic, with low systolic velocities and an absence of diastolic flow.
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