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Fluorouracil has been given systemically for anal, breast, colorectal, oesophageal, stomach, pancreatic and skin cancers (especially head and neck cancers). [12] It has also been given topically (on the skin) for actinic keratoses, skin cancers and Bowen's disease [12] (a type of cutaneous squamous-cell carcinoma), and as eye drops for treatment of ocular surface squamous neoplasia. [13]
Urea cream is indicated for debridement and promotion of normal healing of skin areas with hyperkeratosis, particularly where healing is inhibited by local skin infection, skin necrosis, fibrinous or itching debris or eschar. [5] Specific condition with hyperkeratosis where urea cream is useful include: Dry skin and rough skin [5] Dermatitis [5]
Topical cream formulation is an emulsion semisolid dosage form that is used for skin external application. Most of the topical cream formulations contain more than 20 per cent of water and volatiles and/or less than 50 per cent of hydrocarbons , waxes , or polyethylene glycols as the vehicle for external skin application. [ 1 ]
Topical creams, such as 5-fluorouracil or imiquimod, may require daily application to affected skin areas over a typical time course of weeks. [ 13 ] Cryotherapy is frequently used for few and well-defined lesions, [ 14 ] but undesired skin lightening, or hypopigmentation, may occur at the treatment site. [ 15 ]
In a 2012 review, Riahi and Cohen describe the characteristics of laptop computer-induced erythema ab igne. [5] Temperatures between 43 and 47 °C can cause this skin condition; modern laptops can generate temperatures in this range. Indeed, laptops with powerful processors can reach temperatures of 50 °C and be associated with burns.
Topical steroids are the topical forms of corticosteroids.Topical steroids are the most commonly prescribed topical medications for the treatment of rash and eczema.Topical steroids have anti-inflammatory properties and are classified based on their skin vasoconstrictive abilities. [1]
Burns that affect only the superficial skin layers are known as superficial or first-degree burns. [ 2 ] [ 11 ] They appear red without blisters, and pain typically lasts around three days. [ 2 ] [ 11 ] When the injury extends into some of the underlying skin layer, it is a partial-thickness or second-degree burn . [ 2 ]
Unguentine is an over-the-counter topical antiseptic ointment produced by Lee Pharmaceuticals. It was introduced in 1893 as the first antiseptic surgical dressing ointment by Norwich Pharmaceuticals, who later brought Pepto Bismol to market.
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